(Q34421358)

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2 November 2019

title

The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation (English)

1 reference

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2 November 2019

2

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2 November 2019

author name string

G J Clark

1

1 reference

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2 November 2019

K Rogers-Graham

3

1 reference

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2 November 2019

S M Sebti

4

1 reference

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2 November 2019

A D Hamilton

5

1 reference

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2 November 2019

C J Der

6

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2 November 2019

language of work or name

English

0 references

publication date

1 April 1997

1 reference

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Journal of Biological Chemistry

2 November 2019

published in

1 reference

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2 November 2019

volume

272

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2 November 2019

issue

16

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2 November 2019

page(s)

10608-10615

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Proteins regulating Ras and its relatives

2 November 2019

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The many roads that lead to Ras.

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The GTPase superfamily: conserved structure and molecular mechanism

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The Ras signal transduction pathway

21 January 2018

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The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

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A human oncogene of the RAS superfamily unmasked by expression cDNA cloning

21 January 2018

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Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

21 January 2018

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Characterization and expression of the human rhoH12 gene product

21 January 2018

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Microinjection of recombinant p21rho induces rapid changes in cell morphology

21 January 2018

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

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A role for Rho in Ras transformation

21 January 2018

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An essential role for Rac in Ras transformation

21 January 2018

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The effector interactions of p21ras

21 January 2018

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Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

21 January 2018

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

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Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

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Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases

21 January 2018

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Two distinct Raf domains mediate interaction with Ras

21 January 2018

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TC21 causes transformation by Raf-independent signaling pathways

21 January 2018

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R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

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Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

21 January 2018

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Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.

21 January 2018

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21 January 2018

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Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations

21 January 2018

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

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Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

21 January 2018

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Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

21 January 2018

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Protein prenylation: more than just glue?

21 January 2018

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Lipid modifications and function of the ras superfamily of proteins

21 January 2018

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Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated

21 January 2018

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Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

21 January 2018

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Construction and applications of a highly transmissible murine retrovirus shuttle vector

21 January 2018

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Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

21 January 2018

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Biological assays for Ras transformation

21 January 2018

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

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Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function

21 January 2018

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Prenylation analysis of bacterially expressed and insect cell-expressed Ras and Ras-related proteins

21 January 2018

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

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Analysis of Ras protein expression in mammalian cells

21 January 2018

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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Integrin activation by R-ras.

21 January 2018

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21 January 2018

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Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes

21 January 2018

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Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex

21 January 2018

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Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

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ralGDS family members interact with the effector loop of ras p21.

21 January 2018

1 reference

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Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

21 January 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

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Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

21 January 2018

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Predisposition to neoplastic transformation caused by gene replacement of H-ras1.

21 January 2018

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Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

21 January 2018

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Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.16.10608

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099708%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference