(Q34338299)

1 August 2017

title

Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity (English)

1 reference

1 August 2017

1

Jessica C Fanzo

1 reference

1 August 2017

Wen Yang

2

1 reference

1 August 2017

So Young Jang

3

1 reference

1 August 2017

Sanjay Gupta

4

1 reference

1 August 2017

Qinzhong Chen

5

1 reference

1 August 2017

Ayesha Siddiq

6

1 reference

1 August 2017

Steven Greenberg

7

1 reference

1 August 2017

Alessandra B Pernis

8

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1 August 2017

language of work or name

English

0 references

publication date

9 February 2006

1 reference

Journal of Clinical Investigation

1 August 2017

published in

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1 August 2017

volume

116

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1 August 2017

issue

3

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1 August 2017

page(s)

703-714

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Cellular and genetic mechanisms of self tolerance and autoimmunity

1 August 2017

cites work

1 reference

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Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV

6 July 2018

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Hormonal modulation of B cell development and repertoire selection

6 July 2018

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T-cell tolerance and autoimmunity to systemic and tissue-restricted self-antigens

6 July 2018

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The role of BH3-only proteins in the immune system

6 July 2018

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T lymphocytes in systemic lupus erythematosus: an update

6 July 2018

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Lupus-like autoimmunity caused by defects in T-cell signal transduction

6 July 2018

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Control of T cell viability

6 July 2018

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Role of Bcl-2 family members in immunity and disease

6 July 2018

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Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

6 July 2018

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Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Activation-induced cell death in T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Intrinsic T Cell Defects in Systemic Autoimmunity

6 July 2018

1 reference

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GTPases and T cell activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Interferon gamma is required for activation-induced death of T lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Understanding Rho/Rac biology in T-cells using animal models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Molecular mechanisms of activated T cell death in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

The enemy within: keeping self-reactive T cells at bay in the periphery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

MAP kinases in the immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Dbl family guanine nucleotide exchange factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Vav proteins, adaptors and cell signaling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Deficiency of small GTPase Rac2 affects T cell activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Partners in transcription: NFAT and AP-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Rho signals to cell growth and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

The immunological synapse.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Information transfer at the immunological synapse.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Sex hormones and systemic lupus erythematosus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Signal transduction by the TCR for antigen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Human lupus T cells resist inactivation and escape death by upregulating COX-2.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

A mechanism underlying STAT4-mediated up-regulation of IFN-gamma induction inTCR-triggered T cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Cellular, intracellular, and developmental expression patterns of murine SWAP-70.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1361345

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

27 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

Impaired IgE response in SWAP-70-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

Deficient gamma-interferon production in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16470246

12 December 2020

Identifiers

DOI

10.1172/JCI24096

1 reference

1 August 2017

1 reference

1 August 2017

1 reference