(Q34303172)

1 August 2017

title

Progeria: translational insights from cell biology (English)

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1 August 2017

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3

Francis S Collins

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1 August 2017

1

Leslie B Gordon

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1 August 2017

Kan Cao

2

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1 August 2017

language of work or name

English

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publication date

1 October 2012

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1 August 2017

published in

Journal of Cell Biology

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1 August 2017

volume

199

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1 August 2017

issue

1

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1 August 2017

page(s)

9-13

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describes a project that uses

1 August 2017

HGADFN167

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cites work

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Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome

6 July 2018

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Differential temporal and spatial progerin expression during closure of the ductus arteriosus in neonates

6 July 2018

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Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

6 July 2018

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Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

6 July 2018

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Hutchinson-Gilford progeria is a skeletal dysplasia

6 July 2018

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Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

6 July 2018

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A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

6 July 2018

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Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.

6 July 2018

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A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

6 July 2018

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

6 July 2018

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Phenotype and course of Hutchinson-Gilford progeria syndrome

6 July 2018

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The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

6 July 2018

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A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

6 July 2018

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Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging

6 July 2018

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Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome

6 July 2018

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Lamin A-dependent nuclear defects in human aging

6 July 2018

1 reference

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Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome

6 July 2018

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A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

6 July 2018

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Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

6 July 2018

1 reference

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Genomic instability in laminopathy-based premature aging

6 July 2018

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Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

6 July 2018

1 reference

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Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

6 July 2018

1 reference

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4D imaging to assay complex dynamics in live specimens

6 July 2018

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Photobleaching and photoactivation: following protein dynamics in living cells

6 July 2018

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Lighting up cells: labelling proteins with fluorophores

6 July 2018

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

6 July 2018

1 reference

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Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201207072

Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201207072

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

21 January 2018

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Crossref

https://api.crossref.org/works/10.1083%2FJCB.201207072

Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23027899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201207072

1 reference

1 August 2017

1 reference

1 August 2017

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