(Q34261945)

1 August 2017

title

Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes (English)

1 reference

1 August 2017

G D Demetri

1

1 reference

1 August 2017

T J Ernst

2

1 reference

1 August 2017

E S Pratt

3

1 reference

1 August 2017

B W Zenzie

4

1 reference

1 August 2017

J G Rheinwald

5

1 reference

1 August 2017

J D Griffin

6

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 October 1990

1 reference

Journal of Clinical Investigation

1 August 2017

published in

1 reference

1 August 2017

volume

86

1 reference

1 August 2017

issue

4

1 reference

1 August 2017

page(s)

1261-1269

1 reference

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Studies of a human mesothelioma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

An activated rasN gene: detected in late but not early passage human PA1 teratocarcinoma cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Resistance of human cells to tumorigenesis induced by cloned transforming genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Mechanism of activation of a human oncogene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Partial nucleotide sequence of the 300-nucleotide interspersed repeated human DNA sequences

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Isolation of high-molecular-weight DNA from mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Autocrine growth factors and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Regulation of expression of human granulocyte/macrophage colony-stimulating factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

High frequency of N-ras activation in acute myelogenous leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Autocrine stimulation of interleukin 1 beta in acute myelogenous leukemia cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

The human hematopoietic colony-stimulating factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Transcriptional and posttranscriptional control of c-fos gene expression in human monocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Interleukin-1 regulation of hematopoietic growth factor production by human stromal fibroblasts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Regulation of cytokine gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Regulation of the production and function of granulocytes and monocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Frequency of molecular alterations affecting ras protooncogenes in human urinary tract tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Interleukin 1 gene expression in adult T cell leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Human cell lines that elaborate colon-stimulating activity for the marrow cells of man and other species

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Regulation of the cytoskeleton in mesothelial cells: Reversible loss of keratin and increase in vimentin during rapid growth in culture

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296857

Regulation of granulocyte- and monocyte-colony stimulating factor mRNA levels in human blood monocytes is mediated primarily at a post-transcriptional level

28 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

IL-1 beta production in cultured human monocytes is regulated at multiple levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Expression of ras proto-oncogene proteins in normal human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Activation of the c-fos serum-response element by the activated c-Ha-ras protein in a manner independent of protein kinase C and cAMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Production of interleukin 1 alpha-like factor and colony-stimulating factor by a squamous cell carcinoma of the thyroid (T3M-5) derived from a patient with hypercalcemia and leukocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Induction of membrane-associated interleukin 1 by tumor necrosis factor in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Recombinant human TNF alpha stimulates production of granulocyte colony-stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Normal human mesothelial cells and fibroblasts transfected with the EJras oncogene become EGF-independent, but are not malignantly transformed

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Independent regulation of M-CSF and G-CSF gene expression in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

In vitro expression of colony-stimulating factor genes by human acute myeloblastic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Interleukin-1, tumor necrosis factor, and the production of colony-stimulating factors by cultured mesenchymal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Hemopoietic growth factors: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2212010

12 December 2020

Identifiers

DOI

10.1172/JCI114833

1 reference

1 August 2017

1 reference

1 August 2017

1 reference