(Q34224637)

31 July 2017

title

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (English)

1 reference

genome-wide association study

31 July 2017

main subject

0 references

author

Peter Würtz

98

1 reference

31 July 2017

137

Peter Vollenweider

0 references

Gérard Waeber

127

Gérard Waeber

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André Uitterlinden

91

Andre G Uitterlinden

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Henry Völzke

138

Henry Völzke

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Unnur Þorsteinsdóttir

125

Unnur Thorsteinsdottir

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Cornelia M. van Duijn

113

Cornelia M van Duijn

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David Schlessinger

81

David Schlessinger

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Anna-Liisa Hartikainen

48

Anna-Liisa Hartikainen

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Serena Sanna

8

Serena Sanna

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Jouke-Jan Hottenga

15

Jouke-Jan Hottenga

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Gonneke Willemsen

97

Gonneke Willemsen

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Anneli Pouta

75

Anneli Pouta

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Aimo Ruokonen

79

Aimo Ruokonen

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Philippe Froguel

114

Philippe Froguel

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Inga Prokopenko

77

Inga Prokopenko

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Manuela Uda

126

Manuela Uda

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Christa Meisinger

117

Christa Meisinger

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Angela Döring

39

Angela Döring

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Henri Wallaschofski

95

Henri Wallaschofski

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Mika Ala-Korpela

135

Mika Ala-Korpela

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Nancy L Heard-Costa

14

Nancy L Heard-Costa

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Mark Lathrop

60

Mark Lathrop

1 reference

31 July 2017

29

Gudmar Thorleifsson

1 reference

31 July 2017

Bram P Prins

76

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Mark N. Wass

Mark N Wass

5

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Udo Seedorf

Udo Seedorf

83

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Wolfram Goessling

Wolfram Goessling

45

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Behrooz Z. Alizadeh

Behrooz Z Alizadeh

30

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Toby Johnson

Toby Johnson

55

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Chris Wallace

Chris Wallace

94

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Daníel F. Guðbjartsson

Daniel F Gudbjartsson

46

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Koichi Matsuda

Koichi Matsuda

115

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Lachlan Coin

Lachlan J Coin

11

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Gonçalo Abecasis

Goncalo R Abecasis

108

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Gideon M. Hirschfield

Gideon M Hirschfield

50

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Nita G. Forouhi

Nita G Forouhi

43

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Christian Gieger

Christian Gieger

13

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Hugh Christian Watkins

Hugh Watkins

130

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Ronald P. Stolk

Ronald P Stolk

123

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Markus M Lerch

Markus M Lerch

61

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Ramachandran S. Vasan

Ramachandran S Vasan

93

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Nick Martin

Nicholas G Martin

66

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Paul F. O'Reilly

Paul F O'Reilly

23

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Mark Caulfield

Mark Caulfield

111

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Grant W. Montgomery

Grant W Montgomery

68

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Francesco Cucca

Francesco Cucca

35

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Kirsi H Pietiläinen

Kirsi H Pietiläinen

119

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Paul Elliott

Paul Elliott

142

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Antti J Kangas

Antti J Kangas

56

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Tamara B. Harris

47

Tamara B Harris

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31 July 2017

74

Brenda W Penninx

1 reference

31 July 2017

Mark I McCarthy

116

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Nicholas J. Wareham

128

Nicholas J Wareham

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31 July 2017

65

Ruth J F Loos

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31 July 2017

51

Albert Hofman

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31 July 2017

110

Dorret I Boomsma

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31 July 2017

136

Kari Stefansson

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31 July 2017

37

Eco J C de Geus

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31 July 2017

32

Ingrid B Borecki

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31 July 2017

Marjo-Riitta Järvelin

141

Marjo-Riitta Järvelin

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31 July 2017

69

Patricia B Munroe

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31 July 2017

Jacqueline C M Witteman

132

Jacqueline C M Witteman

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31 July 2017

96

H-Erich Wichmann

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31 July 2017

143

Jaspal S Kooner

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31 July 2017

89

Tanya M Teslovich

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31 July 2017

129

Dawn M Waterworth

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31 July 2017

140

James Scott

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31 July 2017

139

Eric E Schadt

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31 July 2017

Laura M Yerges-Armstrong

100

Laura M Yerges-Armstrong

1 reference

31 July 2017

87

Timothy D Spector

1 reference

31 July 2017

134

Caroline S Fox

1 reference

ORCID Public Data File 2021

31 July 2017

1 reference

Rafn Benediktsson

1 reference

ORCID Public Data File 2021

Reedik Mägi

1 reference

ORCID Public Data File 2021

Harold Snieder

121

Harold Snieder

1 reference

31 July 2017

67

Miriam F Moffatt

1 reference

31 July 2017

Elizabeth K Speliotes

27

Elizabeth K Speliotes

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31 July 2017

131

John B Whitfield

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31 July 2017

Sebastian E Baumeister

10

Sebastian E Baumeister

1 reference

31 July 2017

24

John F Peden

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31 July 2017

40

Georg Ehret

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31 July 2017

53

Elina Hyppönen

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31 July 2017

Christopher J O'Donnell

72

Christopher J O'Donnell

1 reference

31 July 2017

Melanie M. Van der Klauw

92

Melanie M Van der Klauw

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31 July 2017

Bruce H Wolffenbuttel

133

Bruce H R Wolffenbuttel

1 reference

31 July 2017

21

Pedro Marques Vidal

1 reference

31 July 2017

19

Liming Liang

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31 July 2017

118

Vincent Mooser

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31 July 2017

12

Guohong Deng

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31 July 2017

18

Vasiliki Lagou

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31 July 2017

36

Debashish Das

1 reference

31 July 2017

3

Joban Sehmi

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31 July 2017

109

Kourosh R Ahmadi

1 reference

31 July 2017

42

Martin Farrall

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31 July 2017

122

Michael J E Sternberg

1 reference

31 July 2017

52

Georg Homuth

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31 July 2017

44

Nele Friedrich

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31 July 2017

7

Hilma Holm

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31 July 2017

73

Isleifur Olafsson

1 reference

31 July 2017

80

Markku J Savolainen

1 reference

31 July 2017

70

Kiran Musunuru

1 reference

31 July 2017

16

Brigitte Kühnel

1 reference

31 July 2017

26

Pasi Soininen

1 reference

31 July 2017

22

Irene Mateo Leach

1 reference

31 July 2017

9

Maryam Kavousi

1 reference

31 July 2017

57

Ido P Kema

1 reference

31 July 2017

86

Johannes H Smit

1 reference

31 July 2017

34

Pimphen Charoen

1 reference

31 July 2017

120

Gunter Schumann

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31 July 2017

90

Taru Tukiainen

1 reference

31 July 2017

Katherine A Siminovitch

85

Katherine A Siminovitch

1 reference

31 July 2017

71

Yusuke Nakamura

1 reference

31 July 2017

25

Nilufer Rahmioglu

1 reference

31 July 2017

64

Jing-Ping Lin

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31 July 2017

99

Chun Xu

1 reference

31 July 2017

31

Larry D Atwood

1 reference

31 July 2017

John C Chambers

1

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31 July 2017

Weihua Zhang

2

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31 July 2017

Xinzhong Li

4

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31 July 2017

Pim Van der Harst

6

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31 July 2017

Vinod Kumar

17

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31 July 2017

Jian'an Luan

20

1 reference

31 July 2017

Xin Yuan

28

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31 July 2017

Morris J Brown

33

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31 July 2017

Anna L Dixon

38

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31 July 2017

Gudmundur I Eyjolfsson

41

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31 July 2017

Simon Heath

49

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31 July 2017

Harry L A Janssen

54

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31 July 2017

Jens P Kühn

58

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31 July 2017

Sandra Lai

59

1 reference

31 July 2017

Yun Li

62

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31 July 2017

T Jake Liang

63

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31 July 2017

Ralf Puls

78

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31 July 2017

Jeoffrey N L Schouten

82

1 reference

31 July 2017

Srijita Sen-Chowdhry

84

1 reference

31 July 2017

Wenting Tan

88

1 reference

31 July 2017

Alcohol Genome-wide Association (AlcGen) Consortium

101

1 reference

31 July 2017

Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study

102

1 reference

31 July 2017

Genetic Investigation of Anthropometric Traits (GIANT) Consortium

103

1 reference

31 July 2017

Global Lipids Genetics Consortium

104

1 reference

31 July 2017

Genetics of Liver Disease (GOLD) Consortium

105

1 reference

31 July 2017

International Consortium for Blood Pressure (ICBP-GWAS)

106

1 reference

31 July 2017

Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC)

107

1 reference

31 July 2017

William O Cookson

112

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31 July 2017

Howard C Thomas

124

1 reference

31 July 2017

language of work or name

English

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publication date

16 October 2011

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31 July 2017

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31 July 2017

volume

43

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31 July 2017

issue

11

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31 July 2017

page(s)

1131-1138

1 reference

describes a project that uses

31 July 2017

genome-wide association study

1 reference

based on heuristic

inferred from title

cites work

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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

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5 July 2018

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Decreased survival of subjects with elevated liver function tests during a 28-year follow-up.

5 July 2018

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Prediction of metabolic syndrome by low serum testosterone levels in men: results from the study of health in Pomerania

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Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

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Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

5 July 2018

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Genome-wide association study identifies eight loci associated with blood pressure

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

5 July 2018

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Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

5 July 2018

1 reference

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Common variants of FUT2 are associated with plasma vitamin B12 levels

5 July 2018

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Mapping the genetic architecture of gene expression in human liver

5 July 2018

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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

5 July 2018

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The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

5 July 2018

1 reference

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Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

5 July 2018

1 reference

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Genetics of gene expression and its effect on disease

5 July 2018

1 reference

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Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

A second generation human haplotype map of over 3.1 million SNPs

5 July 2018

1 reference

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Exploring the extremes of sequence/structure space with ensemble fold recognition in the program Phyre

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

A genome-wide association study of global gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Evaluation and management of obesity-related nonalcoholic fatty liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Principal components analysis corrects for stratification in genome-wide association studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

The MONICA Augsburg surveys--basis for prospective cohort studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Characterization of mutations in ATP8B1 associated with hereditary cholestasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Human susceptibility and resistance to Norwalk virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

The St. Thomas' UK Adult Twin Registry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Functional expression of the canalicular bile salt export pump of human liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

The mammalian Sec6/8 complex interacts with Ca(2+) signaling complexes and regulates their activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Evaluation of abnormal liver-enzyme results in asymptomatic patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Mouse glycosylphosphatidylinositol-specific phospholipase D (Gpld1) characterization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Risk of gastric cancer and peptic ulcers in relation to ABO blood type: a cohort study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Netherlands Twin Register: from twins to twin families

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Gamma-glutamyl transpeptidase in glutathione biosynthesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Idiosyncratic liver injury: challenges and approaches.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Twin Studies in Finland 2006

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482372

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22001757

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Diagnostic value of serum gamma-glutamyl transferase isoenzyme for hepatocellular carcinoma: a 10-year study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22001757

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.970

1 reference

31 July 2017

1 reference

31 July 2017

1 reference