(Q34172726)

31 July 2017

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title

Clinical pharmacokinetics of clonidine (English)

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31 July 2017

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Lowenthal DT

1

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31 July 2017

Matzek KM

series ordinal

2

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31 July 2017

MacGregor TR

series ordinal

3

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31 July 2017

publication date

1 May 1988

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Clinical Pharmacokinetics

31 July 2017

published in

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31 July 2017

volume

14

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31 July 2017

issue

5

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31 July 2017

page(s)

287-310

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Clonidine in the central nervous system: site and mechanism of hypotensive action

31 July 2017

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Intravenous clonidine in hypertensive patients

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Bullous Dermatosis of Hemodialysis

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of transdermal drug delivery

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Hemodialysis hypotension is not the result of uremic peripheral autonomic neuropathy

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Reduced renovascular resistance by clonidine

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine hydrochloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose.

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

The Therapeutic Uses of Clonidine

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Human cardiovascular adjustments to exercise and thermal stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Nomogram for drug dosage adjustment in patients with renal failure

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https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Radioimmunoassay for clonidine in human plasma and urine using a solid phase second antibody separation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Bioavailability and clinical effects of three brands of clonidine: the relationship between plasma level and effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Effects of transdermal clonidine in young and elderly patients with mild hypertension: evaluation by three noninvasive methods of blood pressure measurement

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Efficacy of clonidine as transdermal therapeutic system: the international clinical trial experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of oral sustained release clonidine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Blood circulation studies with 2-(2,6-dichlorphenylamino)-2-imidazoline hydrochloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine kinetics in man‐evidence for dose dependency and changed pharmacokinetics during chronic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacology of Clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Autonomic insufficiency in uremia as a cause of hemodialysis-induced hypotension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Determination of clonidine in human plasma by glass capillary gas chromatography with electron-capture detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetic and pharmacodynamic studies of oral clonidine in normotensive subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

A newly developed precise and sensitive radioimmunoassay for clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics and side-effects of clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine application: long-term results in essential hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of transdermally delivered clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Alpha- and Beta-Adrenoceptor Changes in Patients on Maintenance Hemodialysis1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Percutaneous absorption in the aged

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Renin and aldosterone suppression in the antihypertensive action of clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Relationship of Immunoassayable Clonidine Plasma Levels to its Pharmacologic Action in Clinical and Experimental Hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Abrupt cessation of treatment in hypertension: Consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics and pharmacodynamics of transdermally administered clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of clonidine and its relation to the hypotensive effect in patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal Administration of Clonidine for Treatment of High BP

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Circulatory effects at rest and exercise of clonidine, an imidazoline derivative with hypotensive properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Effects of acute and chronic treatment with clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

The effect of insulin induced hypoglycaemia on plasma renin activity and urinary catecholamines before and following clonidine (Catapresan) in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

New aspects of the pharmacokinetics and pharmacodynamics of clonidine in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Hemodynamic and Cardiac Effects of Clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Relationship between the cardiovascular effects and steady-state kinetics of clonidine in hypertension. Demonstration of a therapeutic window in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of nitroglycerin and clonidine delivered by the transdermal route

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Circadian rhythm in sweating and cutaneous blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine poisoning. A complex problem.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetic interpretation of the plasma levels of clonidine following transdermal delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Effects of clonidin and chlorthalidone on blood pressure and glucose tolerance in hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of clonidine during pregnancy and nursing

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal antihypertensive therapy: clinical and metabolic considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

The measurement of clonidine in human plasma and urine by combined gas chromatography mass spectrometry with ammonia chemical ionization

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine and the Kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

New aspects of the clinical pharmacology of clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine therapy in hypertensive patients. Effects on office and ambulatory recorded blood pressure values

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine in mild hypertension. A randomized, double-blind, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

The use of transcutaneous clonidine hydrochloride in the patient with diabetes mellitus and mild hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Plasma clonidine concentration and pharmacologic effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Metabolic degradation of clonidine (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Drug therapy in renal failure: dosing guidelines for adults. Part II: sedatives, hypnotics, and tranquilizers; cardiovascular, antihypertensive, and diuretic agents; miscellaneous agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Baroreflex Sensitivity in Patients on Long-Term Haemodialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Plasma clonidine in relation to blood pressure, catecholamines, and renin activity during long-term treatment of hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Role of renin and aldosterone suppression in the antihypertensive mechanism of clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Relationship between plasma concentrations of clonidine and mean arterial pressure during an accidental clonidine overdose

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clinical efficacy and pharmacokinetics of clonidine in hemodialysis and renal insufficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clinical pharmacology and pharmacokinetics of clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Antihypertensive Effect of Clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacodynamic Effects of a New Antihypertensive Drug, Catapres (ST-155)

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal continuous antihypertensive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal administration of clonidine: a new approach to antihypertensive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

The central hypotensive effect of clonidine; Studies in tetraplegie subjcets

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clinical experience with rate-controlled delivery of antihypertensive therapy by a transdermal system

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine in patients with diabetes and mild hypertension.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Initial therapy for hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Mass transport Phenomena and Models: Theoretical Concepts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics and concentration-effect relationships of intervenous and oral clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Dose-response of clonidine on plasma catecholamines in the hypernoradrenergic state associated with vasodilator beta-blocker therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Clonidine, a centrally acting sympathetic inhibitor, as monotherapy for mild to moderate hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Transdermal clonidine for hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Studies on the possible contribution of a peripheral presynaptic action of clonidine and dopamine to their vascular effects under in vivo conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics and pharmacodynamics of clonidine in varying states of renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Effect of clonidine therapy on renal hemodynamics in renal transplant hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Determination of submicrogram quantities of clonidine in biological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Evidence for a renal alpha-adrenergic receptor inhibiting renin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Pharmacokinetics of drug permeation through human skin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Regional hemodynamic effects of clonidine in congestive heart failure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Hypertension associated with clonidine ingestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Limb blood flow: rest and heavy exercise in sitting and supine positions in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Discontinuation Syndrome Following Cessation of Treatment with Clonidine and Other Antihypertensive Agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Plasma clonidine levels in hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Central α-adrenergic systems as targets for hypotensive drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Development of a RIA for clonidine and its comparison with the reference methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

Cutaneous Manifestations of Hyperlipidemia and Uremia

1 reference

https://pubmed.ncbi.nlm.nih.gov/3293868

12 December 2020

10.2165/00003088-198814050-00002

Identifiers

DOI

1 reference

Dimensions Publication ID

31 July 2017

1043113831

0 references

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