(Q34142593)

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Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis

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1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Attenuated familial adenomatous polyposis

0 references

author name string

L K Su

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

C J Barnes

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

W Yao

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Y Qi

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

P M Lynch

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

G Steinbach

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

3 August 2000

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

American Journal of Human Genetics

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

67

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

582-590

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Identification and classification of p53-regulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

The oncogenic activation of beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Variable phenotype of familial adenomatous polyposis in pedigrees with 3' mutation in the APC gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Genotype-phenotype correlations in attenuated adenomatous polyposis coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Germline mutations in the 3' part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Lessons from hereditary colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Association of the APC tumor suppressor protein with catenins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Alleles of the APC gene: an attenuated form of familial polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Mutations of the APC (adenomatous polyposis coli) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Alternatively spliced adenomatous polyposis coli (APC) gene transcripts that delete exons mutated in attenuated APC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Hereditary cancer, oncogenes, and antioncogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Suppression of human colorectal carcinoma cell growth by wild-type p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Identification of deletion mutations and three new genes at the familial polyposis locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Identification of FAP locus genes from chromosome 5q21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

APC mutations occur early during colorectal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Hereditary flat adenoma syndrome: a variant of familial adenomatous polyposis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

5 July 2018

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

28 October 2018

Attenuated familial adenomatous polyposis (AFAP). A phenotypically and genotypically distinctive variant of FAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

28 October 2018

Molecular diagnosis of familial adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1287518

28 October 2018

Attenuated familial adenomatous polyposis due to a mutation in the 3' part of the APC gene. A clue for understanding the function of the APC protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel germline mutations in the APC gene and their phenotypic spectrum in familial adenomatous polyposis kindreds

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic instability of the APC I1307K allele in colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for the determination of epithelial cell kinetic parameters of human colonic epithelium isolated from surgical and biopsy specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alleles of APC modulate the frequency and classes of mutations that lead to colon polyps

1 reference

https://pubmed.ncbi.nlm.nih.gov/10924409

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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