(Q34139532)

31 July 2017

title

Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. (English)

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31 July 2017

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Ellen Weisberg

1

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31 July 2017

Christina Boulton

2

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31 July 2017

Louise M Kelly

3

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31 July 2017

Paul Manley

4

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31 July 2017

Doriano Fabbro

5

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31 July 2017

Thomas Meyer

6

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31 July 2017

D Gary Gilliland

7

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31 July 2017

James D Griffin

8

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31 July 2017

publication date

1 June 2002

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31 July 2017

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31 July 2017

volume

1

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31 July 2017

issue

5

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31 July 2017

page(s)

433-443

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

31 July 2017

cites work

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

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Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

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Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia

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Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan

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FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

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Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)

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7 January 2021

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

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7 January 2021

Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia

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A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations

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7 January 2021

Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

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7 January 2021

Cell differentiation in acute myeloid leukemia.

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7 January 2021

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

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7 January 2021

Phase I and pharmacokinetic study of PKC412, an inhibitor of protein kinase C.

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7 January 2021

Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene

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7 January 2021

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

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7 January 2021

Inhibition of FLT3-mediated transformation by use of a tyrosine kinase inhibitor

1 reference

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7 January 2021

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

1 reference

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7 January 2021

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900069-7

7 January 2021

10.1016/S1535-6108(02)00069-7

Identifiers

DOI

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31 July 2017

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