(Q33953013)

30 July 2017

title

Histone deacetylase inhibitors reduce polyglutamine toxicity (English)

1 reference

30 July 2017

A McCampbell

1

1 reference

30 July 2017

A A Taye

2

1 reference

30 July 2017

L Whitty

3

1 reference

30 July 2017

E Penney

4

1 reference

30 July 2017

J S Steffan

5

1 reference

30 July 2017

K H Fischbeck

6

1 reference

30 July 2017

language of work or name

English

0 references

publication date

11 December 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

98

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30 July 2017

issue

26

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30 July 2017

page(s)

15179-15184

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Altered transcription in yeast expressing expanded polyglutamine

30 July 2017

cites work

1 reference

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

5 July 2018

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SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein

5 July 2018

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Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy

5 July 2018

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Stimulation of CREB binding protein nucleosomal histone acetyltransferase activity by a class of transcriptional activators

5 July 2018

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Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors

5 July 2018

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Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

5 July 2018

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Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.

5 July 2018

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CREB-binding protein sequestration by expanded polyglutamine

5 July 2018

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

5 July 2018

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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation

5 July 2018

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

5 July 2018

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Cell cycle arrest enhances the in vitro cellular toxicity of the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch

5 July 2018

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Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

5 July 2018

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Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7

5 July 2018

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Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

5 July 2018

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Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone

5 July 2018

1 reference

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Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

5 July 2018

1 reference

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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

5 July 2018

1 reference

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Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression

5 July 2018

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Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

5 July 2018

1 reference

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CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1

5 July 2018

1 reference

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Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

5 July 2018

1 reference

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

5 July 2018

1 reference

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Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

5 July 2018

1 reference

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CREB-binding protein in androgen receptor-mediated signaling

5 July 2018

1 reference

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Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

5 July 2018

1 reference

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Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome.

5 July 2018

1 reference

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

5 July 2018

1 reference

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Recruitment of p300/CBP in p53-dependent signal pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Transcriptional activation modulated by homopolymeric glutamine and proline stretches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

In vitro measurement of cytosol and cell nuclear androgen receptors in male rat brain and pituitary

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Embryonic mouse spinal cord motor neuron hybrid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=65003

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

The p300/CBP family: integrating signals with transcription factors and chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Intracellular aggregate formation of dentatorubral-pallidoluysian atrophy (DRPLA) protein with the extended polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Co-activators and co-repressors in the integration of transcriptional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

An expanded CAG repeat sequence in spinocerebellar ataxia type 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261400698

Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA)

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/11742087

12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11742087

12 December 2020

Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/11742087

12 December 2020

Regulation of CBP-mediated transcription by neuronal calcium signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11742087

12 December 2020

Identifiers

DOI

10.1073/PNAS.261400698

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference