(Q33951373)

30 July 2017

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title

Signaling by type I and II cytokine receptors: ten years after (English)

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ORCID Public Data File 2021

30 July 2017

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Doug Hilton

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ORCID Public Data File 2021

author name string

Gadina M

1

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30 July 2017

Hilton D

2

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30 July 2017

Johnston JA

3

1 reference

30 July 2017

Morinobu A

4

1 reference

30 July 2017

Lighvani A

5

1 reference

30 July 2017

Zhou YJ

6

1 reference

30 July 2017

Visconti R

7

1 reference

30 July 2017

O'Shea JJ

8

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30 July 2017

language of work or name

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1 June 2001

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Current Opinion in Immunology

30 July 2017

published in

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30 July 2017

volume

13

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30 July 2017

issue

3

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30 July 2017

page(s)

363-373

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

30 July 2017

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Cytokine receptor signalling

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7 January 2021

Jaks and STATs: biological implications

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7 January 2021

How cells respond to interferons

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7 January 2021

The Janus kinase family of protein tyrosine kinases and their role in signaling

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7 January 2021

Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

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7 January 2021

General classes and functions of four-helix bundle cytokines

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7 January 2021

The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif

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7 January 2021

Interleukin 20: discovery, receptor identification, and role in epidermal function

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7 January 2021

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin

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7 January 2021

Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains

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7 January 2021

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

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7 January 2021

A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling

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7 January 2021

Computational and functional analysis of the putative SH2 domain in Janus Kinases

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7 January 2021

Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction

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7 January 2021

Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain

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7 January 2021

Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model

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7 January 2021

T cell development and activation in Jak3-deficient mice

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7 January 2021

Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice

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7 January 2021

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

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7 January 2021

Mutations in the gene for the IL-7 receptor result in T(-)B(+)NK(+) severe combined immunodeficiency disease

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7 January 2021

A profound deficiency in thymic progenitor cells in mice lacking Jak3.

1 reference

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7 January 2021

Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development

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7 January 2021

Cutting edge: two distinct mechanisms lead to impaired T cell homeostasis in Janus kinase 3- and CTLA-4-deficient mice

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7 January 2021

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

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7 January 2021

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

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7 January 2021

SOCS3 is essential in the regulation of fetal liver erythropoiesis

1 reference

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7 January 2021

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

1 reference

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7 January 2021

Partial impairment of cytokine responses in Tyk2-deficient mice

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7 January 2021

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

1 reference

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7 January 2021

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

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7 January 2021

The biology of Stat4 and Stat6

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7 January 2021

Three-dimensional structure of the Stat3beta homodimer bound to DNA

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7 January 2021

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

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7 January 2021

The role of STATs in transcriptional control and their impact on cellular function

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7 January 2021

Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription

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7 January 2021

Structure of the amino-terminal protein interaction domain of STAT-4

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7 January 2021

Serine phosphorylation of STATs

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7 January 2021

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

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7 January 2021

p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons

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7 January 2021

Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19.

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7 January 2021

Stat5a serine phosphorylation. Serine 779 is constitutively phosphorylated in the mammary gland, and serine 725 phosphorylation influences prolactin-stimulated in vitro DNA binding activity.

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7 January 2021

Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.

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7 January 2021

Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation.

1 reference

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7 January 2021

Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor

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7 January 2021

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

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7 January 2021

Type 1 IFNs and regulation of TH1 responses: enigmas both resolved and emerge

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7 January 2021

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

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7 January 2021

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

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7 January 2021

Immune response in Stat2 knockout mice

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7 January 2021

Roles of STAT3 defined by tissue-specific gene targeting

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7 January 2021

STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation

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7 January 2021

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7 January 2021

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7 January 2021

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

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7 January 2021

IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites

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7 January 2021

Recruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2

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7 January 2021

Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.

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7 January 2021

Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation

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7 January 2021

Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses

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7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

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7 January 2021

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

1 reference

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7 January 2021

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

1 reference

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7 January 2021

STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells.

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7 January 2021

Negative regulators of cytokine signal transduction

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7 January 2021

Negative regulation of cytokine signaling pathways

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7 January 2021

Negative regulation of cytokine signaling: STAT-induced STAT inhibitor

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7 January 2021

Twenty proteins containing a C-terminal SOCS box form five structural classes

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7 January 2021

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

1 reference

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7 January 2021

Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

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7 January 2021

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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7 January 2021

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

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7 January 2021

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

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7 January 2021

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

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7 January 2021

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

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7 January 2021

Gigantism in mice lacking suppressor of cytokine signalling-2

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7 January 2021

Dual effects of suppressor of cytokine signaling (SOCS-2) on growth hormone signal transduction

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7 January 2021

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

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7 January 2021

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

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7 January 2021

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

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7 January 2021

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation

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7 January 2021

Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

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7 January 2021

Modulation of STAT signaling by STAT-interacting proteins

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7 January 2021

Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling

1 reference

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7 January 2021

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

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7 January 2021

Lipid phosphatases in the immune system

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7 January 2021

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

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7 January 2021

10.1016/S0952-7915(00)00228-4

Identifiers

DOI

1 reference

30 July 2017

1 reference