(Q33944410)

30 July 2017

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title

Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B. (English)

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Human T-lymphotropic virus 1

30 July 2017

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K T Jeang

1

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30 July 2017

publication date

1 June 2001

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Cytokine and Growth Factor Reviews

30 July 2017

published in

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30 July 2017

volume

12

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30 July 2017

issue

2-3

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30 July 2017

page(s)

207-217

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Human T cell leukemia virus type I (HTLV-I) and human diseases

30 July 2017

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Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

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Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a

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Induction of the HTLV-I LTR by Jun occurs through the Tax-responsive 21-bp elements

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Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

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Molecular interactions between HTLV-1 Tax protein and the NF-kappa B/kappa B transcription complex

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Divergent Subcellular Locations of HTLV-I Tax and Int-6: A Contrast between in vitro Protein-Protein Binding and Intracellular Protein Colocalization

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Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein

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Cytoplasmic forms of human T-cell leukemia virus type 1 Tax induce NF-kappaB activation

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Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factors

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The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein

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Differential activation of viral and cellular promoters by human T-cell lymphotropic virus-1 tax and cAMP-responsive element modulator isoforms

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Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats

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Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

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https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Act1, an NF-kappa B-activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFkappaB or CREB/ATF activation fail to transform primary human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Kinase-inducible domain-like region of HTLV type 1 tax is important for NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2800%2900028-9

7 January 2021

10.1016/S1359-6101(00)00028-9

Identifiers

DOI

1 reference

30 July 2017

1 reference