(Q33857220)

29 July 2017

title

Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus (English)

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29 July 2017

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S A Litherland

1

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29 July 2017

X T Xie

2

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29 July 2017

A D Hutson

3

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29 July 2017

C Wasserfall

4

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29 July 2017

D S Whittaker

5

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29 July 2017

J X She

6

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29 July 2017

A Hofig

7

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29 July 2017

M A Dennis

8

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29 July 2017

K Fuller

9

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29 July 2017

R Cook

10

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29 July 2017

D Schatz

11

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29 July 2017

L L Moldawer

12

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29 July 2017

M J Clare-Salzler

13

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29 July 2017

language of work or name

English

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publication date

1 August 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

104

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29 July 2017

issue

4

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29 July 2017

page(s)

515-523

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Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

29 July 2017

cites work

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The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens

5 July 2018

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Interleukin 2 and its receptors: recent advances and new immunological functions

5 July 2018

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Endotoxin signal transduction in macrophages.

5 July 2018

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The Th1/Th2 balance in autoimmunity

5 July 2018

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Yes, but do they still get headaches?

5 July 2018

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The inability to process a self-peptide allows autoreactive T cells to escape tolerance

5 July 2018

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Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes

5 July 2018

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Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation?

5 July 2018

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

5 July 2018

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Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Specific suppression by prostaglandin E2 of activation-induced apoptosis of human CD4+CD8+ T lymphoblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Insulin mediated processes in platelets, erythrocytes and monocytes/macrophages: effects of essential fatty acid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Genetic control of autoimmune diabetes in the NOD mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Two mechanisms of antigen-specific apoptosis of myelin basic protein (MBP)-specific T lymphocytes derived from multiple sclerosis patients and normal individuals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Regional distribution of prostanoids in rat brain: effect of insulin and 2-deoxyglucose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Peripheral selection of the T cell repertoire

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Basic principles of ROC analysis

5 July 2018

1 reference

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Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Increase in simultaneous coexpression of naive and memory lymphocyte markers at diagnosis of IDDM.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Evidence for a differential avidity model of T cell selection in the thymus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408519

Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. National Diabetes Data Group

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Increased release of prostaglandins from the mesenteric vascular bed of diabetic animals: the effects of glucose and insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Suppression of concanavalin A-induced responses in splenic lymphocytes by activated macrophages in the non-obese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Functional analysis of cloned macrophage hybridomas. VII. Modulation of suppressor T cell-inducing activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Suppression of autologous mixed leukocyte reaction in type 1 diabetes mellitus by in vivo-activated T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Distinction between immunogenicity and tolerogenicity among HBcAg T cell determinants. Influence of peptide-MHC interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Cellular immune dysfunction in the NOD mouse: suppression of concanavalin A-induced responses in spleen cells by activated macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2R alpha gene expression at multiple levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Enhanced metabolism of arachidonic acid by macrophages from nonobese diabetic (NOD) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Defective T cell receptor/CD3 complex signaling in human type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Accessory cell-derived IL-12 and prostaglandin E2 determine the IFN-gamma level of activated human CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

The Hemodynamic Abnormalities in Short-Term Insulin Deficiency: The Role of Prostaglandin Inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Genetics of insulin-dependent diabetes; non-major histocompatibility genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

IGF-I and insulin amplify IL-1 beta-induced nitric oxide and prostaglandin biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

The mouse macrophage activation-associated marker protein, p71/73, is an inducible prostaglandin endoperoxide synthase (cyclooxygenase)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometric enzyme immunoassays

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Essential Fatty Acid Deficiency Prevents Autoimmune Diabetes in Nonobese Diabetic Mice Through a Positive Impact on Antigen-Presenting Cells and Th2 Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10449443

12 December 2020

Identifiers

DOI

10.1172/JCI4852

1 reference

29 July 2017

1 reference

29 July 2017

1 reference