(Q33745140)

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16 January 2020

title

FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy (English)

1 reference

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16 January 2020

0 references

1 reference

Theodorus H Van der Kwast

5

1 reference

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16 January 2020

4

Bas W G van Rhijn

1 reference

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16 January 2020

author name string

Lucie C Kompier

1

1 reference

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16 January 2020

Irene Lurkin

2

1 reference

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16 January 2020

Madelon N M van der Aa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072204%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Ellen C Zwarthoff

6

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

3 November 2010

1 reference

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16 January 2020

1 reference

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16 January 2020

volume

5

1 reference

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16 January 2020

issue

11

1 reference

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16 January 2020

page(s)

e13821

1 reference

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Creative Commons Attribution 4.0 International

16 January 2020

copyright license

start time

3 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers

21 June 2018

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PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer

21 June 2018

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PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies

21 June 2018

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Bladder cancer biomarkers and their role in surveillance and screening

21 June 2018

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

21 June 2018

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Molecular pathogenesis and diagnostics of bladder cancer

21 June 2018

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Detection of tumours of the urinary tract in voided urine

21 June 2018

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Biomarkers for detection and surveillance of bladder cancer.

21 June 2018

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FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours.

21 June 2018

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EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder

21 June 2018

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Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis

21 June 2018

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Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

21 June 2018

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Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer

21 June 2018

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Ras and phosphoinositide 3-kinase: partners in development and tumorigenesis

21 June 2018

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Patients' perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison

21 June 2018

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21 June 2018

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21 June 2018

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Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern

21 June 2018

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FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer

21 June 2018

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Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.

21 June 2018

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Rare cancer-specific mutations in PIK3CA show gain of function

21 June 2018

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PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

21 June 2018

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PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors.

21 June 2018

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Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene.

21 June 2018

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Ras, PI(3)K and mTOR signalling controls tumour cell growth

21 June 2018

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Understanding urothelial carcinoma through cancer pathways

21 June 2018

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 June 2018

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21 June 2018

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Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells

21 June 2018

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21 June 2018

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Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth.

21 June 2018

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Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.

21 June 2018

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Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma

21 June 2018

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The health economics of bladder cancer: a comprehensive review of the published literature.

21 June 2018

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The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3

21 June 2018

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Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

21 June 2018

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Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation

21 June 2018

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 June 2018

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Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein

21 June 2018

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The clinical epidemiology of superficial bladder cancer. Dutch South-East Cooperative Urological Group

21 June 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 June 2018

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Medicare Payments from Diagnosis to Death for Elderly Cancer Patients by Stage at Diagnosis

21 June 2018

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Expression of ras p21 oncogene product on human bladder tumors

21 June 2018

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Correlation between the expression of the P21 ras oncogene product and the biological behavior of bladder tumors

21 June 2018

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Clonal origin of bladder cancer

21 June 2018

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Epidermal growth factor receptor and bladder cancer: a review

21 June 2018

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The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour.

21 June 2018

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Patient opinion of urinary tests versus flexible urethrocystoscopy in follow-up examination for superficial bladder cancer: a utility analysis

21 January 2018

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Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome

21 January 2018

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FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma

21 January 2018

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Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer

21 January 2018

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FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.

21 January 2018

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FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of solar lentigo

21 January 2018

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A phase III, multicenter comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder cancer.

21 January 2018

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Improved detection and treatment of bladder cancer using hexaminolevulinate imaging: a prospective, phase III multicenter study

21 January 2018

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Functional differences between two classes of oncogenic mutation in the PIK3CA gene

21 January 2018

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CK20 and Ki-67 as significant prognostic factors in human bladder carcinoma.

21 January 2018

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Evaluation of pain caused by urethrocystoscopy in patients with superficial bladder cancer: a perspective of quality of life.

30 October 2018

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Molecular evolution of multiple recurrent cancers of the bladder

30 October 2018

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12 December 2020

1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer

1 reference

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12 December 2020

Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway

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12 December 2020

FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder

1 reference

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12 December 2020

A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine

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12 December 2020

Phosphatidylinositol 3-kinase/akt and ras/raf-mitogen-activated protein kinase pathway mutations in anaplastic thyroid cancer

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12 December 2020

Considerations on implementing diagnostic markers into clinical decision making in bladder cancer

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12 December 2020

MIP-1alpha (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma

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12 December 2020

Long-term follow-up of noninvasive bladder tumours (stage Ta): recurrence and progression

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12 December 2020

TNM Classification of Malignant Tumors, fifth edition (1997). Union Internationale Contre le Cancer and the American Joint Committee on Cancer

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12 December 2020

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

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12 December 2020

Allelic losses demonstrate monoclonality of multifocal bladder tumors

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12 December 2020

Correlation between the expression of oncogenes ras and c-erbB-2 and the biological behavior of bladder tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21072204

12 December 2020

Prognostic significance of p27Kip1expression in bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21072204

12 December 2020

10.1371/JOURNAL.PONE.0013821

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072204%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21072204%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

21072204

1 reference