(Q30490795)

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Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

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Europe PubMed Central

PMC publication ID

20 August 2017

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

pancreatic cancer

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Ravi P Sahu

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Ruifen Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Sanjay Batra

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Yan Shi

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Sanjay K Srivastava

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

23 June 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

30

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1744-1753

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Silibinin inhibits glioma cell proliferation via Ca2+/ROS/MAPK-dependent mechanism in vitro and glioma tumor growth in vivo

1 reference

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The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate

1 reference

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Tiron, a ROS scavenger, protects human lung cancer Calu-6 cells against antimycin A-induced cell death.

1 reference

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In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway

1 reference

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trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways

1 reference

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Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis

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Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells

1 reference

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Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.

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Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier

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Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells

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Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents

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Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation

1 reference

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20 June 2018

Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.

1 reference

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20 June 2018

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

1 reference

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20 June 2018

Targeting ROS: selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound

1 reference

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20 June 2018

Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK.

1 reference

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Regulation of cyclin-dependent kinase 5 and p53 by ERK1/2 pathway in the DNA damage-induced neuronal death

1 reference

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20 June 2018

Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells

1 reference

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20 June 2018

Role of nongenomic activation of phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase 1/2 pathways in 1,25D3-mediated apoptosis in squamous cell car

1 reference

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20 June 2018

N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells

1 reference

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Regulation of protein function by glutathionylation

1 reference

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20 June 2018

Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species.

1 reference

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Cancer statistics, 2005

1 reference

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20 June 2018

A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation

1 reference

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20 June 2018

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis

1 reference

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20 June 2018

Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest

1 reference

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20 June 2018

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

1 reference

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20 June 2018

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

1 reference

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20 June 2018

Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis

1 reference

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Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.

1 reference

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AGA technical review on the epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. American Gastroenterological Association

1 reference

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Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism

1 reference

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Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16.

1 reference

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Dietary factors and the risk of pancreatic cancer: a case-control study in Shanghai China.

1 reference

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20 June 2018

Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms

1 reference

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Intake of foods and nutrients and cancer of the exocrine pancreas: a population-based case-control study in The Netherlands

1 reference

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A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

1 reference

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Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

1 reference

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20 June 2018

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo

1 reference

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21 January 2018

Benzyl isothiocyanate modifies expression of the G2/M arrest-related genes

1 reference

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21 January 2018

Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells

1 reference

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21 January 2018

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

1 reference

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21 January 2018

Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways

1 reference

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21 January 2018

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

1 reference

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21 January 2018

Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells

1 reference

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21 January 2018

Sodium orthovanadate potentiates EGCG-induced apoptosis that is dependent on the ERK pathway

1 reference

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21 January 2018

ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells.

1 reference

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21 January 2018

Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells.

1 reference

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26 November 2018

Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrients and pancreatic cancer: a population-based case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19549704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CARCIN/BGP157

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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