(Q30175931)

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7 December 2019

title

Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation (English)

1 reference

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7 December 2019

9

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7 December 2019

author name string

A M Cheng

1

1 reference

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7 December 2019

T M Saxton

2

1 reference

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7 December 2019

R Sakai

3

1 reference

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7 December 2019

S Kulkarni

4

1 reference

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7 December 2019

G Mbamalu

5

1 reference

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7 December 2019

W Vogel

6

1 reference

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7 December 2019

C G Tortorice

7

1 reference

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7 December 2019

R D Cardiff

8

1 reference

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7 December 2019

W J Muller

10

1 reference

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7 December 2019

T Pawson

11

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7 December 2019

language of work or name

English

0 references

publication date

1 December 1998

1 reference

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7 December 2019

1 reference

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7 December 2019

volume

95

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7 December 2019

issue

6

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7 December 2019

page(s)

793-803

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Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

7 December 2019

cites work

1 reference

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7 January 2021

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

1 reference

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7 January 2021

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

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7 January 2021

The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation.

1 reference

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7 January 2021

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

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7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

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7 January 2021

Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.

1 reference

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7 January 2021

Requirement of FGF-4 for postimplantation mouse development

1 reference

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7 January 2021

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

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7 January 2021

Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

1 reference

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7 January 2021

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

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7 January 2021

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

1 reference

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7 January 2021

Nuk controls pathfinding of commissural axons in the mammalian central nervous system

1 reference

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7 January 2021

In vivo functional analysis of the Ras exchange factor son of sevenless

1 reference

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7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

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7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

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7 January 2021

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1 reference

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7 January 2021

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

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7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

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7 January 2021

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

1 reference

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7 January 2021

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

1 reference

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7 January 2021

A novel viral oncogene with structural similarity to phospholipase C

1 reference

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7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

1 reference

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7 January 2021

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

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7 January 2021

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

1 reference

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7 January 2021

Intermediate filament protein synthesis in preimplantation murine embryos

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7 January 2021

Signaling through scaffold, anchoring, and adaptor proteins

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7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

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7 January 2021

Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila.

1 reference

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7 January 2021

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

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7 January 2021

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1 reference

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7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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7 January 2021

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

1 reference

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

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7 January 2021

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

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7 January 2021

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

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7 January 2021

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

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7 January 2021

The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling

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7 January 2021

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

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7 January 2021

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

1 reference

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7 January 2021

The Grb2 binding domain of mSos1 is not required for downstream signal transduction

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7 January 2021

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development

1 reference

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7 January 2021

Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis

1 reference

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7 January 2021

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

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7 January 2021

Differentiation of F9 embryonal carcinoma cells induced by the c-jun and activated c-Ha-ras oncogenes

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7 January 2021

10.1016/S0092-8674(00)81702-X

Identifiers

DOI

1 reference

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7 December 2019

1 reference