(Q29619280)

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

scientific article (publication date: November 1995)

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7584144

30 April 2017

immunoconjugates

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7584144

24 May 2024

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A. H. Sharpe

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24 May 2024

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E. A. Tivol

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24 May 2024

F. Borriello

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24 May 2024

A. N. Schweitzer

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24 May 2024

W. P. Lynch

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24 May 2024

J. A. Bluestone

5

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24 May 2024

language of work or name

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30 April 2017

publication date

November 1995

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30 April 2017

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https://doi.org/10.1016/1074-7613(95)90125-6

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24 May 2024

https://api.elsevier.com/content/article/PII:1074761395901256?httpAccept=text/xml

1 reference

10.1016/1074-7613(95)90125-6

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24 May 2024

https://api.elsevier.com/content/article/PII:1074761395901256?httpAccept=text/plain

1 reference

10.1016/1074-7613(95)90125-6

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24 May 2024

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7584144

30 April 2017

3

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30 April 2017

5

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30 April 2017

541-7

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7584144

30 April 2017

CTLA-4 can function as a negative regulator of T cell activation

1 reference

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B70 antigen is a second ligand for CTLA-4 and CD28.

1

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Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance

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Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.

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Treatment of murine lupus with CTLA4Ig

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Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

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Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production

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Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice

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The B7 and CD28 receptor families

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

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Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

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Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia.

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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The mouse Pgk-1 gene promoter contains an upstream activator sequence

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Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

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CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

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A negative regulatory function of B7 revealed in B7-1 transgenic mice

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Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

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10.1016/1074-7613(95)90125-6

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7584144

30 April 2017

Consolidated OpenCitations Corpus – April 2017

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