(Q29617097)

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25 December 2019

title

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 (English)

2 references

PubMed

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17277771

30 April 2017

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25 December 2019

1 reference

5

1 reference

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25 December 2019

author name string

Emilie Vander Haar

1

1 reference

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25 December 2019

Seong-Il Lee

2

1 reference

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25 December 2019

Sricharan Bandhakavi

3

1 reference

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25 December 2019

Timothy J Griffin

4

1 reference

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25 December 2019

language of work or name

1 reference

30 April 2017

publication date

4 February 2007

1 reference

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25 December 2019

2 references

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30 April 2017

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25 December 2019

volume

9

2 references

PubMed

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30 April 2017

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25 December 2019

issue

3

2 references

PubMed

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30 April 2017

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25 December 2019

page(s)

316-323

1 reference

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

25 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Rheb binds and regulates the mTOR kinase

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Genetics: influence of TOR kinase on lifespan in C. elegans

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Tsc2 is not a critical target of Akt during normal Drosophila development

1 May 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Mammalian TOR: a homeostatic ATP sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Effects of rapamycin in the Eker rat model of tuberous sclerosis complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Genetic interaction of Lobe with its modifiers in dorsoventral patterning and growth of the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

Integration of growth factor and nutrient signaling: implications for cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

inferred from DOI database lookup

7 January 2021

based on heuristic

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

1 reference

https://api.crossref.org/works/10.1038%2FNCB1547

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17277771

30 April 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17277771%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 December 2019

1050216585

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17277771

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017