(Q28578096)

31 January 2017

title

Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein (English)

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protein heterodimerization activity

31 January 2017

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GOA release 2020-03-11

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H. Kasahara

1

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31 January 2017

A. Usheva

2

1 reference

31 January 2017

T. Ueyama

3

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31 January 2017

H. Aoki

4

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31 January 2017

N. Horikoshi

5

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31 January 2017

S. Izumo

6

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31 January 2017

language of work or name

English

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publication date

16 February 2001

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

276

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31 January 2017

issue

7

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31 January 2017

page(s)

4570–4580

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https://api.crossref.org/works/10.1074%2FJBC.M004995200

31 January 2017

1 reference

What determines the specificity of action of Drosophila homeodomain proteins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis

21 January 2018

1 reference

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RNA binding and translational suppression by bicoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Nuclear import of the homeodomain protein extradenticle in response to Wg and Dpp signalling.

21 January 2018

1 reference

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The Drosophila engrailed protein is phosphorylated by a serine-specific protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Cooperative dimerization of paired class homeo domains on DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

A homeodomain protein related to caudal regulates intestine-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Homeodomain Proteins: Cooperating to be different

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Congenital heart disease caused by mutations in the transcription factor NKX2-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Drosophila NK-homeobox genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

NK-2 homeobox genes and heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Csx: a murine homeobox-containing gene specifically expressed in the developing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Dimerization of a specific DNA-binding protein on the DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Gene regulation: protein escorts to the transcription ball

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

DNA specificity enhanced by sequential binding of protein monomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

The three-dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

D-mef2 is a target for Tinman activation during Drosophila heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

BMP-4-responsive regulation of dorsal–ventral patterning by the homeobox protein Mix.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004995200

21 January 2018

Identifiers

DOI

10.1074/JBC.M004995200

1 reference

31 January 2017

1 reference