(Q28509294)

24 January 2017

title

Role for Akt3/protein kinase Bgamma in attainment of normal brain size (English)

1 reference

Thymoma viral proto-oncogene 3

24 January 2017

0 references

1 reference

Thymoma viral proto-oncogene 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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Morris J. Birnbaum

13

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Argiris Efstratiadis

12

object named as

Argiris Efstratiadis

1 reference

24 January 2017

Rachael M. Easton

1

1 reference

24 January 2017

Han Cho

2

1 reference

24 January 2017

Kristin Roovers

3

1 reference

24 January 2017

Diana W. Shineman

4

1 reference

24 January 2017

Moshe Mizrahi

5

1 reference

24 January 2017

Mark S. Forman

6

1 reference

24 January 2017

Virginia M.-Y. Lee

7

1 reference

24 January 2017

Matthias Szabolcs

8

1 reference

24 January 2017

Ron de Jong

9

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24 January 2017

Tilman Oltersdorf

10

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24 January 2017

Thomas Ludwig

11

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24 January 2017

language of work or name

English

0 references

publication date

1 March 2005

1 reference

Molecular and Cellular Biology

24 January 2017

published in

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24 January 2017

volume

25

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24 January 2017

issue

5

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24 January 2017

page(s)

1869–1878

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How are the sizes of cells, organs, and bodies controlled?

24 January 2017

cites work

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

19 March 2017

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Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

19 March 2017

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

19 March 2017

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

19 March 2017

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Protein kinase B alpha/Akt1 regulates placental development and fetal growth

19 March 2017

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Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

19 March 2017

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The phosphoinositide 3-kinase pathway

19 March 2017

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

19 March 2017

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A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

19 March 2017

1 reference

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Size control in animal development

19 March 2017

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Disruption of IRS-2 causes type 2 diabetes in mice

19 March 2017

1 reference

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

19 March 2017

1 reference

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

7 April 2017

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Role of insulin-like growth factors in embryonic and postnatal growth

7 April 2017

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

7 April 2017

1 reference

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Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Advances in protein kinase B signalling: AKTion on multiple fronts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Body building: regulation of shape and size by PI3K/TOR signaling during development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The insulin-like growth factor system and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

PTEN regulation of neural development and CNS stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Genetic analysis of insulin signaling in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Akt/protein kinase B promotes organ growth in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Distinct and overlapping functions of insulin and IGF-I receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

PKB/AKT: functional insights from genetic models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Genetic control of cell size

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Increased number of cardiomyocytes in cross-sections from tachycardia-induced cardiomyopathic hearts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Comparative aspects of the brain growth spurt

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 and identification of insulin receptor substrate-2.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

IGF-I is required for normal embryonic growth in mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Control of synaptic strength, a novel function of Akt.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Insulin-like growth factor 1 is essential for normal dendritic growth

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Raf and akt mediate distinct aspects of sensory axon growth

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Drosophila S6 kinase: a regulator of cell size

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Biochemical and morphometric analyses show that myelination in the insulin-like growth factor 1 null brain is proportionate to its neuronal composition.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

The Drosophila insulin receptor is required for normal growth

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

Relative brain size and basal metabolic rate in terrestrial vertebrates

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=549378

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15713641

12 December 2020

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15713641

12 December 2020

The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/15713641

12 December 2020

Genetics of mouse growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/15713641

12 December 2020

10.1128/MCB.25.5.1869-1878.2005

Identifiers

DOI

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