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Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2

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Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2 (English)

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author name string

R J Turesky

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1

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A Constable

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2

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L B Fay

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3

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F P Guengerich

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4

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language of work or name

English

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publication date

1 September 1999

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published in

Cancer Letters

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volume

143

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issue

2

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page(s)

109-12

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cites work

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

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Carcinogenicity of food mutagens

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7 January 2021

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Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.

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Metabolism of the food-borne mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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7 January 2021

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Metabolic activation of a protein pyrolysate promutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat liver microsomes and purified cytochrome P-450

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stated in

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7 January 2021

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MeIQx-DNA adduct formation in rodent and human tissues at low doses

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7 January 2021

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DOI

10.1016/S0304-3835(99)00137-8

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PubMed publication ID

10503887

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(Q28373365)

Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2

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