(Q28300979)

2

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R A Kesterson

3

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V J Hruby

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R D Cone

Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur

5

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language of work or name

English

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publication date

9 January 1997

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published in

Nature

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volume

385

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issue

6612

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page(s)

165-8

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cites work

1 reference

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7 January 2021

Molecular characterization of the mouse agouti locus.

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Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants

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7 January 2021

Structure and function of ASP, the human homolog of the mouse agouti gene

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Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

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7 January 2021

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

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Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin recep

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Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system

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7 January 2021

Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics

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Evidence for two separate opiate peptide neuronal systems

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alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain

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Short-term starvation decreases POMC mRNA but does not alter GnRH mRNA in the brain of adult male rats

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Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats

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Diurnal rhythm in proopiomelanocortin mRNA in the arcuate nucleus of the male rat

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Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse.

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

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The role of neuropeptide Y in the antiobesity action of the obese gene product

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Identification of targets of leptin action in rat hypothalamus

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1 Assay of adenylyl cyclase catalytic activity

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A colorimetric assay for measuring activation of Gs- and Gq-coupled signaling pathways

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Intracerebroventricular injections in mice. Some methodological refinements

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