(Q28242438)

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4 January 2020

title

P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression (English)

1 reference

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4 January 2020

0 references

1 reference

3

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4 January 2020

author name string

David W Salzman

series ordinal

1

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4 January 2020

Jonathan Shubert-Coleman

series ordinal

2

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4 January 2020

language of work or name

English

0 references

publication date

27 August 2007

1 reference

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Journal of Biological Chemistry

4 January 2020

published in

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4 January 2020

volume

282

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4 January 2020

issue

45

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4 January 2020

page(s)

32773-32779

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MicroRNA-cancer connection: the beginning of a new tale

4 January 2020

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Ribo-gnome: the big world of small RNAs

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Mechanisms of gene silencing by double-stranded RNA

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Regulation of the germinal center response by microRNA-155

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MicroRNA genes are transcribed by RNA polymerase II

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The nuclear RNase III Drosha initiates microRNA processing

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The Microprocessor complex mediates the genesis of microRNAs

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The Drosha-DGCR8 complex in primary microRNA processing

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

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Structural basis for double-stranded RNA processing by Dicer

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

21 January 2018

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Purified Argonaute2 and an siRNA form recombinant human RISC

21 January 2018

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

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A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

21 January 2018

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A protein sensor for siRNA asymmetry

21 January 2018

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

21 January 2018

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

21 January 2018

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

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RNA helicase A interacts with RISC in human cells and functions in RISC loading

21 January 2018

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

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MicroRNAs regulate brain morphogenesis in zebrafish

21 January 2018

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The ATPase, RNA unwinding, and RNA binding activities of recombinant p68 RNA helicase

21 January 2018

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RAS is regulated by the let-7 microRNA family

21 January 2018

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Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

21 January 2018

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

21 January 2018

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

21 January 2018

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Substrate requirements for let-7 function in the developing zebrafish embryo

21 January 2018

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SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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ATPase/helicase activities of p68 RNA helicase are required for pre-mRNA splicing but not for assembly of the spliceosome

21 January 2018

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A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

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DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

21 January 2018

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RNA helicase activity associated with the human p68 protein

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M705054200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724023%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference