(Q28235481)

GOA release 2020-03-11

Sirtuin 1

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

3

Toren Finkel

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author name string

Shino Nemoto

series ordinal

1

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Maria M Fergusson

series ordinal

2

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language of work or name

English

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publication date

22 April 2005

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published in

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volume

280

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issue

16

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page(s)

16456-60

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cites work

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

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Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin

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The Sir2 family of protein deacetylases

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Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases

21 January 2018

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The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

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Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

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Calorie restriction extends yeast life span by lowering the level of NADH.

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Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

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Sir2 mediates longevity in the fly through a pathway related to calorie restriction

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Yeast life-span extension by calorie restriction is independent of NAD fluctuation

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

21 January 2018

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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

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Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

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Insights into aging obtained from p53 mutant mouse models

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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Activation of PPARgamma coactivator-1 through transcription factor docking

21 January 2018

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Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

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SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

21 January 2018

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

21 January 2018

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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M501485200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

15716268

1 reference

Consolidated OpenCitations Corpus – April 2017