(Q28218883)

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

scientific article (publication date: 3 September 2002)

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scholarly article

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants (English)

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Nuclear factor, erythroid derived 2, like 2

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GOA release 2020-03-11

Albena Dinkova-Kostova

1

object named as

Albena T Dinkova-Kostova

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8

object named as

Paul Talalay

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W. David Holtzclaw

2

object named as

W David Holtzclaw

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author name string

Robert N Cole

3

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Ken Itoh

4

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Nobunao Wakabayashi

5

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Yasutake Katoh

6

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Masayuki Yamamoto

7

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language of work or name

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publication date

3 September 2002

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Proceedings of the National Academy of Sciences of the United States of America

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99

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18

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11908-13

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Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

1 reference

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1 reference

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20 March 2017

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

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Calculation of protein extinction coefficients from amino acid sequence data

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Nrf2 is essential for protection against acute pulmonary injury in mice

1 reference

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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RsrA, an anti-sigma factor regulated by redox change

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22 April 2017

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

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Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

1 reference

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Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

1 reference

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1 reference

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Mass spectrometry unravels disulfide bond formation as the mechanism that activates a molecular chaperone.

1 reference

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1 reference

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Chemoprotection against cancer by phase 2 enzyme induction

1 reference

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1 reference

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Electrostatic influence of local cysteine environments on disulfide exchange kinetics.

1 reference

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27 November 2018

Identifiers

10.1073/PNAS.172398899

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2002PNAS...9911908D

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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