(Q28208798)

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The Akt-regulated Forkhead Transcription Factor FOXO3a Controls Endothelial Cell Viability through Modulation of the Caspase-8 Inhibitor FLIP

scientific article (publication date: 9 January 2004)

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The Akt-regulated forkhead transcription factor FOXO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP (English)

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The Akt-regulated Forkhead Transcription Factor FOXO3a Controls Endothelial Cell Viability through Modulation of the Caspase-8 Inhibitor FLIP (English)

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10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

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intracellular signaling peptides and proteins

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551207

20 March 2024

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551207

20 March 2024

1 reference

10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

1 reference

10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

2

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Henrike Maatz

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Carsten Skurk

1

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Hyo-Soo Kim

3

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Jiang Yang

4

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Md Ruhul Abid

5

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Kenneth Walsh

7

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William C. Aird

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551207

20 March 2024

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publication date

9 January 2004

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8 October 2003

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551207

20 March 2024

full work available at URL

http://www.jbc.org/article/S0021925818527691/pdf

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14551207

20 March 2024

https://api.elsevier.com/content/article/PII:S0021925818527691?httpAccept=text/xml

1 reference

10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

https://api.elsevier.com/content/article/PII:S0021925818527691?httpAccept=text/plain

1 reference

10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M304736200

1 reference

10.1074/JBC.M304736200

https://api.crossref.org/works/10.1074/JBC.M304736200

20 March 2024

Journal of Biological Chemistry

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279

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2

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1513-25

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Vascular cell apoptosis in remodeling, restenosis, and plaque rupture

1 reference

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The Fas death factor

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Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy

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Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation

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Endothelial cell apoptosis induced by oxidized LDL is associated with the down-regulation of the cellular caspase inhibitor FLIP.

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Oxidized LDL activates fas-mediated endothelial cell apoptosis

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Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

1 reference

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Expression of cellular FLICE-inhibitory protein in human coronary arteries and in a rat vascular injury model

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Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

1 reference

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Role of Akt signaling in vascular homeostasis and angiogenesis

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Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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21 January 2018

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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A simplified system for generating recombinant adenoviruses

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Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

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p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene

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Disruption of epithelial cell-matrix interactions induces apoptosis

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

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Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis

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Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

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DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

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The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

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Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

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PKB/AKT: functional insights from genetic models

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FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

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Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart

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Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway

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Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

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7

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Cancer Research

33

63

468

author name string

LaVallee

publication date

2003

1 reference

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