(Q28207364)

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10 November 2019

review article

1 reference

title

Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism (English)

1 reference

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10 November 2019

1 reference

Giovanni Codacci-Pisanelli

5

1 reference

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10 November 2019

Elisabeth Bloemena

12

1 reference

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10 November 2019

1

G J Peters

1 reference

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10 November 2019

author name string

H H J Backus

2

1 reference

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10 November 2019

S Freemantle

3

1 reference

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10 November 2019

B van Triest

4

1 reference

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10 November 2019

C L van der Wilt

6

1 reference

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10 November 2019

K Smid

7

1 reference

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10 November 2019

J Lunec

8

1 reference

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10 November 2019

A H Calvert

9

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10 November 2019

S Marsh

10

1 reference

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10 November 2019

H L McLeod

11

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10 November 2019

S Meijer

13

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10 November 2019

G Jansen

14

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10 November 2019

C J van Groeningen

15

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10 November 2019

H M Pinedo

16

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10 November 2019

language of work or name

English

0 references

publication date

1 July 2002

1 reference

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Biochimica et Biophysica Acta

10 November 2019

published in

1 reference

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10 November 2019

volume

1587

1 reference

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10 November 2019

issue

2-3

1 reference

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10 November 2019

page(s)

194-205

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The catalytic mechanism and structure of thymidylate synthase

10 November 2019

cites work

1 reference

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7 January 2021

Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma

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7 January 2021

Effect of folate diastereoisomers on the binding of 5-fluoro-2'-deoxyuridine-5'-monophosphate to thymidylate synthase

1 reference

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7 January 2021

Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft

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7 January 2021

Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells

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7 January 2021

Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing

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7 January 2021

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil

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7 January 2021

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

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7 January 2021

Antitumour activity, toxicity and inhibition of thymidylate synthase of prolonged administration of 5-fluorouracil in mice.

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7 January 2021

Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed

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7 January 2021

Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates

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7 January 2021

5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients

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7 January 2021

Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer

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7 January 2021

Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694.

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7 January 2021

Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations.

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7 January 2021

The role of thymidylate synthase as an RNA binding protein

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7 January 2021

Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein

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7 January 2021

Thymidylate synthase from untreated human colorectal cancer and colonic mucosa: Enzyme activity and inhibition by 5-fluoro-2′-deoxyuridine-5′-monophosphate

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7 January 2021

A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil

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7 January 2021

Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases

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7 January 2021

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

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7 January 2021

Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.

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7 January 2021

A gene expression database for the molecular pharmacology of cancer

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7 January 2021

Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.

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7 January 2021

Folate homeostasis and antiproliferative activity of folates and antifolates

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7 January 2021

Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer

1 reference

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7 January 2021

A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil

1 reference

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7 January 2021

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

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7 January 2021

Identification of a thymidylate synthase ribonucleoprotein complex in human colon cancer cells

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7 January 2021

Ligand-mediated induction of thymidylate synthase occurs by enzyme stabilization. Implications for autoregulation of translation

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7 January 2021

5-fluorouracil-mediated thymidylate synthase induction in malignant and nonmalignant human cells

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7 January 2021

In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil

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7 January 2021

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation

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7 January 2021

The effect of different routes of administration of 5-fluorouracil on thymidylate synthase inhibition in the rat

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7 January 2021

New targets for pyrimidine antimetabolites in the treatment of solid tumours. 1: Thymidylate synthase

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7 January 2021

Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase

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7 January 2021

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project

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7 January 2021

Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer.

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7 January 2021

Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells

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7 January 2021

Intracellular location of thymidylate synthase and its state of phosphorylation

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7 January 2021

Thymidylate synthase: a target for combination therapy and determinant of chemotherapeutic response in colorectal cancer

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7 January 2021

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer

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7 January 2021

ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy

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7 January 2021

Molecular predictors of survival after adjuvant chemotherapy for colon cancer

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7 January 2021

10.1016/S0925-4439(02)00082-0

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084461%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017