(Q28198463)

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Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity

scientific article (publication date: 11 June 1999)

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Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity (English)

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author name string

X L Yao

1

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M J Cowan

2

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M T Gladwin

3

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M M Lawrence

4

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C W Angus

5

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J H Shelhamer

6

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publication date

11 June 1999

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Journal of Biological Chemistry

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274

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24

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17202-8

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Lipid second messengers

1 reference

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Phospholipase A2 enzymes: regulation and physiological role.

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A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals

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Expression and characterization of human group V phospholipase A2

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Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.

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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

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A soluble protein characteristic of the nervous system

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The S100 protein family

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Calpactins: two distinct Ca++-regulated phospholipid- and actin-binding proteins isolated from lung and placenta

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Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids

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Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation

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Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells

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Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.

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P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2

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Biochemical Characterization of a 34-Kilodalton Normal Cellular Substrate of pp60v-src and an Associated 6-Kilodalton Protein

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Enhanced expression of group II phospholipase A2 gene in the tissues of endotoxin shock rats and its suppression by glucocorticoid.

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Effects of dexamethasone and transforming growth factor-beta 2 on group II phospholipase A2 mRNA and activity levels in interleukin 1 beta- and forskolin-stimulated mesangial cells

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Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis

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Multiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages.

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Mifepristone (RU486): a review

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Repression of Cyclooxygenase-2 and Prostaglandin E2Release by Dexamethasone Occurs by Transcriptional and Post-transcriptional Mechanisms Involving Loss of Polyadenylated mRNA

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Protein terminology tangle

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