(Q27852999)

13 November 2016

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16 March 2020

title

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies (English)

1 reference

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16 March 2020

1 reference

11

1 reference

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16 March 2020

Aleksandra Sejda

14

1 reference

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16 March 2020

Aik Choon Tan

18

1 reference

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16 March 2020

12

Jacek Jassem

1 reference

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16 March 2020

17

D Ross Camidge

1 reference

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16 March 2020

16

Paul A Bunn

1 reference

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16 March 2020

19

Fred R Hirsch

1 reference

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16 March 2020

3

Dexiang Gao

1 reference

16 March 2020

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Murry W Wynes

1

1 reference

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16 March 2020

Trista K Hinz

2

1 reference

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16 March 2020

Michael Martini

4

1 reference

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16 March 2020

Lindsay A Marek

5

1 reference

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16 March 2020

Kathryn E Ware

6

1 reference

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16 March 2020

Michael G Edwards

7

1 reference

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16 March 2020

Diana Böhm

8

1 reference

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16 March 2020

Sven Perner

9

1 reference

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16 March 2020

Barbara A Helfrich

10

1 reference

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16 March 2020

Szymon Wojtylak

13

1 reference

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16 March 2020

Joseph M Gozgit

15

1 reference

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16 March 2020

Lynn E Heasley

20

1 reference

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16 March 2020

language of work or name

English

0 references

publication date

25 April 2014

1 reference

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16 March 2020

published in

Clinical Cancer Research

1 reference

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16 March 2020

volume

20

1 reference

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16 March 2020

issue

12

1 reference

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16 March 2020

page(s)

3299-3309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771645%20AND%20SRC:MED&resulttype=core&format=json

Ponatinib in refractory Philadelphia chromosome-positive leukemias

16 March 2020

cites work

1 reference

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Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer

20 March 2017

1 reference

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Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Somatic mutations affect key pathways in lung adenocarcinoma

20 March 2017

1 reference

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Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells

20 March 2017

1 reference

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High-resolution genomic profiles of human lung cancer

20 March 2017

1 reference

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Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer

20 March 2017

1 reference

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Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology

20 March 2017

1 reference

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Comprehensive genomic characterization of squamous cell lung cancers

20 March 2017

1 reference

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Fibroblast growth factor signalling: from development to cancer

20 March 2017

1 reference

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A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop.

7 April 2017

1 reference

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Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models

29 September 2017

1 reference

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

29 September 2017

1 reference

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Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Increased insulin-like growth factor 1 receptor protein expression and gene copy number in small cell lung cancer.

29 September 2017

1 reference

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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

29 September 2017

1 reference

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Amplification of chromosomal segment 4q12 in non-small cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

Rationale for treatment of metastatic squamous cell carcinoma of the lung using fibroblast growth factor receptor inhibitors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4062100

10.1158/1078-0432.CCR-13-3060

27 November 2018

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24771645%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

2 references

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16 March 2020

PubMed publication ID

24771645

2 references