(Q27704406)

9

0 references

Henning Stahlberg

17

0 references

Eric S. Fischer

object named as

Eric S Fischer

2

0 references

Richard D Bunker

object named as

Richard D Bunker

3

0 references

Syota Matsumoto

object named as

Syota Matsumoto

15

0 references

author name string

Simone Cavadini

1

0 references

Alessandro Potenza

4

0 references

Gondichatnahalli M Lingaraju

5

0 references

Kenneth N Goldie

6

0 references

Weaam I Mohamed

7

0 references

Mahamadou Faty

8

0 references

Rohan E J Beckwith

10

0 references

Ritesh B Tichkule

11

0 references

Ulrich Hassiepen

12

0 references

Wassim Abdulrahman

13

0 references

Radosav S Pantelic

14

0 references

Kaoru Sugasawa

16

0 references

Nicolas H Thomä

Understanding nucleotide excision repair and its roles in cancer and ageing.

18

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language of work or name

English

0 references

publication date

31 March 2016

0 references

published in

Nature

0 references

volume

531

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issue

7596

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page(s)

598-603

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cites work

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The DNA Damage Response: Making It Safe to Play with Knives

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Human DNA repair genes, 2005.

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UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.

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The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

21 January 2018

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The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

21 January 2018

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DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA.

21 January 2018

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Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

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Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein

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Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA

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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

21 January 2018

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Crystal structure of the human COP9 signalosome

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Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

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DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.

21 January 2018

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Structural assembly of cullin-RING ubiquitin ligase complexes

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

21 January 2018

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UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

21 January 2018

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Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

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Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism

21 January 2018

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Structural basis for a reciprocal regulation between SCF and CSN.

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Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.

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Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes

21 January 2018

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The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

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Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

21 January 2018

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

21 January 2018

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A novel cysteine-rich sequence motif

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

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Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8

21 January 2018

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Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

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Identification of a primary target of thalidomide teratogenicity

21 January 2018

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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

21 January 2018

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Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

21 January 2018

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The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

21 January 2018

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Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

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Substrate-mediated regulation of cullin neddylation

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Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins

21 January 2018

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Resolving the CSN and CAND1 paradoxes

21 January 2018

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Quantifying the local resolution of cryo-EM density maps

21 January 2018

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ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

21 January 2018

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Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

21 January 2018

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Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase

21 January 2018

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12 December 2020

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

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12 December 2020

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

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Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T.

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12 December 2020

Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!

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12 December 2020

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

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12 December 2020