(Q27644895)

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system (English)

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enzyme replacement therapy

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Gaucher's disease

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based on heuristic

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9

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Joel L. Sussman

object named as

Joel L Sussman

10

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Anthony H. Futerman

object named as

Anthony H Futerman

11

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Einat Brill-Almon

5

object named as

Einat Brill-Almon

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author name string

Yoseph Shaaltiel

1

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Daniel Bartfeld

2

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Sharon Hashmueli

3

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Gideon Baum

4

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Gad Galili

6

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Orly Dym

7

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Swetlana A Boldin-Adamsky

8

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David Aviezer

12

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publication date

September 2007

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Plant Biotechnology Journal

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5

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5

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579-90

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Enzyme replacement in Gaucher disease

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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PROCHECK: a program to check the stereochemical quality of protein structures

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Processing of X-ray diffraction data collected in oscillation mode

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Likelihood-enhanced fast rotation functions

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Immunoreactivity in mammals of two typical plant glyco-epitopes, core alpha(1,3)-fucose and core xylose.

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A murine monoclonal antibody produced in transgenic plants with plant-specific glycans is not immunogenic in mice.

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New directions in the treatment of Gaucher disease

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A translational enhancer derived from tobacco mosaic virus is functionally equivalent to a Shine-Dalgarno sequence

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Posttranslational modification of therapeutic proteins in plants

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Enzyme therapy for lysosomal storage disease: principles, practice, and prospects

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Human acid beta-glucosidase: glycosylation is required for catalytic activity

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pGreen: a versatile and flexible binary Ti vector for Agrobacterium-mediated plant transformation

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Plant cell cultures for the production of recombinant proteins

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Gaucher disease: pathological mechanisms and modern management

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N-glycoprotein biosynthesis in plants: recent developments and future trends

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Analyses of variant acid beta-glucosidases: effects of Gaucher disease mutations

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Analysis of glucocerebrosidase activity using N-(1-[14C]hexanoyl)-D-erythroglucosylsphingosine demonstrates a correlation between levels of residual enzyme activity and the type of Gaucher disease

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A short C-terminal sequence is necessary and sufficient for the targeting of chitinases to the plant vacuole

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Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter

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X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease

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Production of correctly processed human serum albumin in transgenic plants

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Expression of a mannosyl-fucosyl receptor for endocytosis on cultured primary macrophages and their hybrids

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Effectiveness of enzyme replacement therapy in 1028 patients with type 1 Gaucher disease after 2 to 5 years of treatment: a report from the Gaucher Registry

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Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

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