(Q27620480)

2

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S S Taremi

3

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W W Prosise

4

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P C Weber

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

5

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publication date

15 November 1999

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published in

Structure

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volume

7

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issue

11

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page(s)

1353-63

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cites work

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Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis

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Structure and organization of the hepatitis C virus genome isolated from human carriers

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Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini

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Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

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A second hepatitis C virus-encoded proteinase

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Mechanism of autoproteolysis at the NS2-NS3 junction of the hepatitis C virus polyprotein

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Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.

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A zinc binding site in viral serine proteinases

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Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex.

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Structure of the hepatitis C virus RNA helicase domain

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

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The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

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Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

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Structural biology of HIV.

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Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

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Rational design and functional expression of a constitutively active single-chain NS4A-NS3 proteinase

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Construction, expression, and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease

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A novel recombinant single-chain hepatitis C virus ns3-ns4a protein with improved helicase activity

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On the size of the active site in proteases. I. Papain

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A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding

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Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures

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Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation

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Engineering aspartic proteases to probe structure and function relationships

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Characterization of a genetically engineered inactivation-resistant coagulation factor VIIIa

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Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding

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Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

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Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus

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Isolation of RNA aptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA.

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Selection of RNA aptamers that bind specifically to the NS3 protease of hepatitis C virus

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U6atac snRNA, the highly divergent counterpart of U6 snRNA, is the specific target that mediates inhibition of AT-AC splicing by the influenza virus NS1 protein

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Hepatitis C: the clinical spectrum of disease

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Processing of X-ray diffraction data collected in oscillation mode

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Checking your imagination: applications of the free R value

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Raster3D: photorealistic molecular graphics

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

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