(Q24634801)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

0 references

0 references

Leber congenital amaurosis

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Samuel G. Jacobson

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Artur V Cideciyan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Tomas S Aleman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Shalesh Kaushal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Sharon B Schwartz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Sanford L Boye

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Elizabeth A M Windsor

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Thomas J Conlon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Alexander Sumaroka

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Ji-Jing Pang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Alejandro J Roman

11

1 reference

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2 February 2020

Barry J Byrne

12

1 reference

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2 February 2020

language of work or name

English

0 references

publication date

1 September 2009

1 reference

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2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

20

1 reference

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2 February 2020

issue

9

1 reference

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2 February 2020

page(s)

999-1004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

2 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Safety and efficacy of gene transfer for Leber's congenital amaurosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Effect of gene therapy on visual function in Leber's congenital amaurosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

RPE65: role in the visual cycle, human retinal disease, and gene therapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Defining the residual vision in leber congenital amaurosis caused by RPE65 mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Leber congenital amaurosis: genes, proteins and disease mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Retinal laminar architecture in human retinitis pigmentosa caused by Rhodopsin gene mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Human cone photoreceptor dependence on RPE65 isomerase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Retinal degenerations: from cell signaling to cell therapy; pre-clinical and clinical issues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Photoreceptor layer topography in children with leber congenital amaurosis caused by RPE65 mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

The association between visual acuity and central retinal thickness in retinitis pigmentosa

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Interocular asymmetry of visual function in heterozygotes of X-linked retinitis pigmentosa

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829287

Variability of visual field measurements in normal subjects and patients with retinitis pigmentosa

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19583479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New visual acuity charts for clinical research

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19583479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Automated Light- and Dark- Adapted Perimetry for Evaluating Retinitis Pigmentosa

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19583479

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/HUM.2009.086

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19583479%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

19583479

2 references