(Q24622553)

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Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial

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27 January 2020

Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial (English)

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27 January 2020

obstetrics and gynaecology

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reproductive medicine

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multicenter clinical trial

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placebo-controlled trial

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based on heuristic

inferred from title

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27 January 2020

Lisa M Sullivan

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George W. Creasy

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27 January 2020

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27 January 2020

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27 January 2020

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27 January 2020

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27 January 2020

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27 January 2020

Ultrasound in Obstetrics and Gynecology

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27 January 2020

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27 January 2020

Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate

1 reference

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7 April 2017

Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): therapeutic cerclage with bed rest versus bed rest alone

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7 April 2017

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

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27 September 2017

The molecular basis for sonographic cervical shortening at term: identification of differentially expressed genes and the epithelial-mesenchymal transition as a function of cervical length

1 reference

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27 September 2017

Clinical significance of early (< 20 weeks) vs. late (20-24 weeks) detection of sonographic short cervix in asymptomatic women in the mid-trimester

1 reference

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27 September 2017

Patients with an asymptomatic short cervix (<or=15 mm) have a high rate of subclinical intraamniotic inflammation: implications for patient counseling

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27 September 2017

The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity

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27 September 2017

Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix

1 reference

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27 September 2017

Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

27 September 2017

Medroxyprogesterone acetate modulates remodeling, immune cell census, and nerve fibers in the cervix of a mouse model for inflammation-induced preterm birth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

27 September 2017

Transvaginal sonographic measurement of cervical length to predict preterm birth in asymptomatic women at increased risk: a systematic review

1 reference

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27 September 2017

Estrogen and progesterone metabolism in the cervix during pregnancy and parturition

1 reference

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27 September 2017

Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo-controlled trial.

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27 September 2017

Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial.

1 reference

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27 September 2017

Progesterone and the risk of preterm birth among women with a short cervix

1 reference

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27 September 2017

Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of progesterone receptor-A.

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27 September 2017

Dynamics of cervical remodeling during pregnancy and parturition: mechanisms and current concepts

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27 September 2017

Is sonographic assessment of cervical length better than digital examination in screening for preterm delivery in a low-risk population?

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27 September 2017

Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-kappaB may contribute to the onset of labor through inhibition of PR function.

1 reference

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27 September 2017

Progesterone receptor isoform (A/B) ratio of human fetal membranes increases during term parturition.

1 reference

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27 September 2017

Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal

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27 September 2017

A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition

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27 September 2017

Early prediction of preterm delivery by transvaginal ultrasonography

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

27 September 2017

Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study

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27 September 2017

Prostaglandins, the fetal membranes and the cervix

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27 September 2017

Cervical length at 16-22 weeks' gestation and risk for preterm delivery

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27 September 2017

The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network

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27 September 2017

Meta-analysis of randomized controlled trials of antenatal corticosteroid for the prevention of respiratory distress syndrome: Discussion

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27 September 2017

The physiology of cervical ripening and cervical dilatation and the effect of abortifacient drugs.

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27 September 2017

Prediction of risk for preterm delivery by ultrasonographic measurement of cervical length

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27 September 2017

Antiprogesterones

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27 September 2017

Confidence intervals for the number needed to treat

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30 May 2018

Regulation of the Uterus and Cervix during Pregnancy and Labor Role of Progesterone and Nitric Oxide

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30 May 2018

Suppression of interleukin 8 production by progesterone in rabbit uterine cervix

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30 May 2018

Relationship between timing of ovariectomy and maintenance of pregnancy in the guinea-pig

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30 May 2018

Ripening of the uterine cervix of the guinea-pig after treatment with the progesterone antagonist onapristone (ZK 98.299): an electron microscopic study

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30 May 2018

Progesterone effects on preterm birth in high-risk pregnancies: a randomized placebo-controlled trial

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28 November 2018

Effect of progesterone on cervical shortening in women at risk for preterm birth: secondary analysis from a multinational, randomized, double-blind, placebo-controlled trial.

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28 November 2018

Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis

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28 November 2018

A randomized controlled trial of cervical scanning vs history to determine cerclage in women at high risk of preterm birth (CIRCLE trial).

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28 November 2018

Nuclear progesterone receptor expression in the human fetal membranes and decidua at term before and after labor

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28 November 2018

AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes

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28 November 2018

Medroxyprogesterone acetate modulates the immune response in the uterus, cervix and placenta in a mouse model of preterm birth.

1 reference

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28 November 2018

Preventing cervical ripening: the primary mechanism by which progestational agents prevent preterm birth?

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28 November 2018

Prevention of spontaneous preterm birth: the role of sonographic cervical length in identifying patients who may benefit from progesterone treatment

1 reference

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28 November 2018

Gestational age at cervical length measurement and incidence of preterm birth

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28 November 2018

Effects of progesterone on iNOS, COX-2, and collagen expression in the cervix

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28 November 2018

Cerclage for prevention of preterm birth in women with a short cervix found on transvaginal ultrasound examination: a randomized trial

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28 November 2018

Cervical cerclage for prevention of preterm delivery in women with short cervix: randomised controlled trial

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28 November 2018

15-hydroxyprostaglandin dehydrogenase and cyclooxygenase 2 messenger ribonucleic acid expression and immunohistochemical localization in human cervical tissue during term and preterm labor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Differential regulation of the progesterone receptor A and B in the human uterine cervix at parturition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Endocrine regulation of cervical ripening in humans--potential roles for gonadal steroids and insulin-like growth factor-I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Revisiting the short cervix detected by transvaginal ultrasound in the second trimester: why cerclage therapy may not help

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Mid-trimester endovaginal sonography in women at high risk for spontaneous preterm birth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Progesterone receptor isoform A inhibits isoform B-mediated transactivation in human amnion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Interactions between progesterone receptor isoforms in myometrial cells in human labour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

The International Conference on Harmonization Good Clinical Practice guideline.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Sonographic measurement of uterine cervix at 18-22 weeks' gestation and the risk of preterm delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

5 alpha-reduced androgens play a key role in murine parturition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Cervical ripening of the rat in dependence on endocrine milieu; effects of antigestagens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482512

28 November 2018

Ultrasound differentiation of the competent from the incompetent cervix: prevention of preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervical length and obstetric history predict spontaneous preterm birth: development and validation of a model to provide individualized risk assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaginal ultrasonographic assessment of cervical length changes during normal pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with an ultrasonographic cervical length < or =15 mm have nearly a 50% risk of early spontaneous preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of some drugs on ripening of uterine cervix in nonpregnant castrated and pregnant rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormones and cervical ripening: dehydroepiandrosterone sulfate, estradiol, estriol, and progesterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cGMP-induced relaxation and cGMP-dependent protein kinase in rat myometrium during pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of progesterone on prostaglandin E(2)-induced changes in glycosaminoglycan synthesis by human cervical fibroblasts in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is treatment with vaginal pessaries an option in patients with a sonographically detected short cervix?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sonographic evaluation of cervical length in pregnancy: diagnosis and management of preterm cervical effacement in patients at risk for premature delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervical ultrasonography compared with manual examination as a predictor of preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACOG Practice Bulletin. Clinical management guidelines for obstetricians-gynecologists. Number 55, September 2004 (replaces practice pattern number 6, October 1997). Management of Postterm Pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervical length at 23 weeks of gestation: prediction of spontaneous preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on the sonographic measurement of cervical length and the risk of premature birth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of sonographic cervical parameters in predicting spontaneous preterm birth in high-risk singleton gestations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervical length and funneling at 23 weeks of gestation in the prediction of spontaneous early preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Trial of 17 Alpha-Hydroxyprogesterone Caproate to Prevent Prematurity in Twins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of mifepristone on cervical ripening and labor induction in primigravidae

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) adopts Consolidated Guideline on Good Clinical Practice in the Conduct of Clinical Trials on Medicinal Products for Human Use

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transvaginal ultrasonographic cervical assessment for the prediction of preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of cervical incompetence by ultrasound

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of progesterone on intracellular Ca2+ homeostasis in human myometrial smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of gemeprost and mifepristone on the mechanical properties of the cervix prior to first trimester termination of pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerclage: we all know how to do it but can't agree when to do it

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cervicovaginal fibronectin and cervical length at 23 weeks of gestation: relative risk of early preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single transvaginal sonographic measurement of cervical length early in the third trimester as a predictor of preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sonographic evaluation of the incompetent cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17-hydroxyprogesterone caproate for twin pregnancy: a double-blind, randomized clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of labor with mifepristone--a randomized, double-blind study versus placebo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of spontaneous preterm delivery from endocervical length at 11 to 13 weeks

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of labor and cervical maturation using mifepristone (RU 486) in the late pregnant rat. Influence of a cyclooxygenase inhibitor (Diclofenac)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parturition defect in steroid 5alpha-reductase type 1 knockout mice is due to impaired cervical ripening

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral plasma progesterone levels during human pregnancy and labor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/UOG.9017

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472815%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472815%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472815%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

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