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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
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Europe PubMed Central
PMC publication ID
316928
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
title
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
glucocorticoid
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phosphorylation
1 reference
based on heuristic
inferred from title
author
Robert M. Nissen
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
author name string
K R Yamamoto
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
316928
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
language of work or name
English
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publication date
1 September 2000
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PMC publication ID
316928
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10 November 2019
published in
Genes & Development
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
14
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
18
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
2314-2329
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stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
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Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ
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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
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Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme
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7 April 2017
An RNA polymerase II holoenzyme responsive to activators
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Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation
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Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases
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7 April 2017
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27 September 2017
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27 September 2017
The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.
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27 September 2017
Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement.
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27 September 2017
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27 September 2017
Stress, corticotropin-releasing hormone, glucocorticoids, and the immune/inflammatory response: acute and chronic effects
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27 September 2017
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27 September 2017
Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme
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27 September 2017
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27 September 2017
Effect of dexamethasone on interleukin-1beta-(IL-1beta)-induced nuclear factor-kappaB (NF-kappaB) and kappaB-dependent transcription in epithelial cells.
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27 September 2017
The histone acetylase PCAF is a nuclear receptor coactivator.
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27 September 2017
A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids
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27 September 2017
Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis
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27 September 2017
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
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27 September 2017
Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation
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27 September 2017
I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.
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27 September 2017
Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae
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27 September 2017
Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus.
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27 September 2017
Analysis of chromatin structure by in vivo formaldehyde cross-linking.
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27 September 2017
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27 September 2017
Mad proteins contain a dominant transcription repression domain.
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27 September 2017
Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern
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27 September 2017
Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis
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27 September 2017
Negative interaction between the RelA(p65) subunit of NF-kappaB and the progesterone receptor
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27 September 2017
Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family
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27 September 2017
Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6.
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27 September 2017
Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor
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27 September 2017
Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions
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27 September 2017
12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter.
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27 September 2017
Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
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27 September 2017
GAL4 interacts with TATA-binding protein and coactivators
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27 September 2017
Common themes in assembly and function of eukaryotic transcription complexes
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27 September 2017
Interaction of GAL4 and GAL80 gene regulatory proteins in vitro
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27 September 2017
Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II
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27 September 2017
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.
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27 September 2017
Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts
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27 September 2017
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression
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27 September 2017
A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor
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27 September 2017
Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.
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27 September 2017
Regulatory crosstalk at composite response elements
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27 September 2017
Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo
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27 September 2017
Multilayered control of intracellular receptor function
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27 September 2017
Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.
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27 September 2017
Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis
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27 September 2017
Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
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27 September 2017
The sensitivity of RNA polymerase II in elongation complexes to C-terminal domain phosphatase
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30 May 2018
Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo
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30 May 2018
Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila melanogaster.
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30 May 2018
Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
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30 May 2018
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30 May 2018
Glucocorticoid-mediated repression of intercellular adhesion molecule-1 expression in human monocytic and bronchial epithelial cell lines
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30 May 2018
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30 May 2018
Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities
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30 May 2018
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30 May 2018
Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.
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30 May 2018
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30 May 2018
Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter
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28 November 2018
Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans
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28 November 2018
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28 November 2018
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28 November 2018
Distinct domains of the RelA NF-kappaB subunit are required for negative cross-talk and direct interaction with the glucocorticoid receptor.
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28 November 2018
Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.
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28 November 2018
A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation
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Yeast carboxyl-terminal domain kinase I positively and negatively regulates RNA polymerase II carboxyl-terminal domain phosphorylation
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Characterization of the Residues Phosphorylatedin Vitroby Different C-terminal Domain Kinases
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A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II
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Binding of liganded vitamin D receptor to the vitamin D receptor interacting protein coactivator complex induces interaction with RNA polymerase II holoenzyme
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Identifiers
DOI
10.1101/GAD.827900
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PMC publication ID
316928
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
10995388
1 reference
stated in
Europe PubMed Central
PMC publication ID
316928
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995388%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ResearchGate publication ID
12328587
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