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Nuclear receptor corepressors
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title
Nuclear receptor corepressors
(English)
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author name string
Mitchell A Lazar
series ordinal
1
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language of work or name
English
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publication date
2003
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published in
Nuclear Receptor Signaling
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volume
1
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page(s)
e001
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cites work
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
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The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2
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PubMed Central
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24 March 2017
The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor
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24 March 2017
Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia
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PubMed Central
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24 March 2017
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation
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24 March 2017
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
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PubMed Central
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24 March 2017
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3
1 reference
stated in
PubMed Central
reference URL
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24 March 2017
Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization
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PubMed Central
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24 March 2017
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness
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PubMed Central
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24 March 2017
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
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PubMed Central
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24 March 2017
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
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PubMed Central
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24 March 2017
Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily
1 reference
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PubMed Central
reference URL
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24 March 2017
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors
1 reference
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PubMed Central
reference URL
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24 March 2017
ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
Transcriptional activation and repression by RORalpha, an orphan nuclear receptor required for cerebellar development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing
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PubMed Central
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24 March 2017
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
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PubMed Central
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24 March 2017
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
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PubMed Central
reference URL
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24 March 2017
Translating the Histone Code
1 reference
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PubMed Central
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24 March 2017
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha
1 reference
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PubMed Central
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24 March 2017
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
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24 March 2017
Signaling network model of chromatin
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PubMed Central
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24 March 2017
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
1 reference
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PubMed Central
reference URL
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24 March 2017
Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
A transcriptional co-repressor that interacts with nuclear hormone receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
Combinatorial roles of the nuclear receptor corepressor in transcription and development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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24 March 2017
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation
1 reference
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PubMed Central
reference URL
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24 March 2017
Acetylation: a regulatory modification to rival phosphorylation?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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7 April 2017
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
1 reference
stated in
PubMed Central
reference URL
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7 April 2017
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
27 September 2017
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors
1 reference
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PubMed Central
reference URL
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27 September 2017
A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis
1 reference
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PubMed Central
reference URL
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27 September 2017
Mechanism of corepressor binding and release from nuclear hormone receptors.
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PubMed Central
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27 September 2017
Molecular determinants of nuclear receptor-corepressor interaction
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PubMed Central
reference URL
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27 September 2017
The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
A novel role for helix 12 of retinoid X receptor in regulating repression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Signal-specific co-activator domain requirements for Pit-1 activation
1 reference
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PubMed Central
reference URL
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27 September 2017
Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
The phantom ligand effect: allosteric control of transcription by the retinoid X receptor
1 reference
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PubMed Central
reference URL
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27 September 2017
The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
27 September 2017
The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat
1 reference
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PubMed Central
reference URL
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27 September 2017
Regulation of gene expression by thyroid hormone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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27 September 2017
Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
30 May 2018
Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
30 May 2018
A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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30 May 2018
Liver X receptors interact with corepressors to regulate gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
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29 November 2018
Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor
1 reference
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PubMed Central
reference URL
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29 November 2018
Multiple N-CoR complexes contain distinct histone deacetylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
29 November 2018
The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
29 November 2018
Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1402229
retrieved
29 November 2018
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist
1 reference
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PubMed Central
reference URL
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retrieved
29 November 2018
Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16604174
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A canonical structure for the ligand-binding domain of nuclear receptors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16604174
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1621/NRS.01001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2918184
Fatcat ID
release_pk6dkewtdna73esuvo57jnzyri
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/pk6dkewtdna73esuvo57jnzyri
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
2918184
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2918184
PMC publication ID
1402229
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2918184
PubMed publication ID
16604174
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2918184
ResearchGate publication ID
7176106
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