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Sorting out the complexity of SR protein functions
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Europe PubMed Central
PMC publication ID
1369994
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
review article
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title
Sorting out the complexity of SR protein functions
(English)
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Europe PubMed Central
PMC publication ID
1369994
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author
Brenton R. Graveley
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1
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Europe PubMed Central
PMC publication ID
1369994
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
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B R Graveley
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1
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English
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publication date
1 September 2000
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Europe PubMed Central
PMC publication ID
1369994
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10 November 2019
published in
RNA
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PMC publication ID
1369994
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10 November 2019
volume
6
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Europe PubMed Central
PMC publication ID
1369994
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10 November 2019
issue
9
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Europe PubMed Central
PMC publication ID
1369994
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
1197-1211
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Europe PubMed Central
PMC publication ID
1369994
reference URL
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10 November 2019
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The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution
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The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing
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24 March 2017
Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing
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24 March 2017
Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing
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24 March 2017
SR proteins: a conserved family of pre-mRNA splicing factors
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24 March 2017
Isolation of a complementary DNA that encodes the mammalian splicing factor SC35
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24 March 2017
A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor
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24 March 2017
The dynamics of a pre-mRNA splicing factor in living cells
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Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors
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7 April 2017
Exon recognition in vertebrate splicing
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Functional characterization of SR and SR-related genes in Caenorhabditis elegans
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27 September 2017
Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases
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Exonic splicing enhancer motif recognized by human SC35 under splicing conditions
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Functional recognition of the 3' splice site AG by the splicing factor U2AF35.
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27 September 2017
SR-related proteins and the processing of messenger RNA precursors
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27 September 2017
Identification of a bidirectional splicing enhancer: differential involvement of SR proteins in 5' or 3' splice site activation
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27 September 2017
The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing
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27 September 2017
Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing
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27 September 2017
Determinants of SR protein specificity.
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27 September 2017
Developmental regulation of SR protein phosphorylation and activity
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27 September 2017
Srp2, an SR protein family member of fission yeast: in vivo characterization of its modular domains
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27 September 2017
An element in the 5' common exon of the NCAM alternative splicing unit interacts with SR proteins and modulates 5' splice site selection
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27 September 2017
A novel family of plant splicing factors with a Zn knuckle motif: examination of RNA binding and splicing activities
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27 September 2017
The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers.
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27 September 2017
Exonic splicing enhancers contribute to the use of both 3' and 5' splice site usage of rat beta-tropomyosin pre-mRNA
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27 September 2017
Antagonism between RSF1 and SR proteins for both splice-site recognition in vitro and Drosophila development.
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27 September 2017
Serine-arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing
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27 September 2017
Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor
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27 September 2017
Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements
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27 September 2017
Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences
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27 September 2017
Multiple distinct splicing enhancers in the protein-coding sequences of a constitutively spliced pre-mRNA.
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27 September 2017
A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.
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27 September 2017
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo
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PubMed Central
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27 September 2017
Analysis of the functional specificity of RS domains in vivo
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27 September 2017
Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing
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27 September 2017
Characterization of SRp46, a novel human SR splicing factor encoded by a PR264/SC35 retropseudogene
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27 September 2017
Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
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27 September 2017
Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors.
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PubMed Central
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27 September 2017
A specific RNA hairpin loop structure binds the RNA recognition motifs of the Drosophila SR protein B52
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27 September 2017
RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins
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PubMed Central
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27 September 2017
Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer
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27 September 2017
Characterization of a novel arginine/serine-rich splicing factor in Arabidopsis
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PubMed Central
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27 September 2017
Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene
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PubMed Central
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27 September 2017
Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer
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PubMed Central
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27 September 2017
Initial splice-site recognition and pairing during pre-mRNA splicing
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PubMed Central
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27 September 2017
Pre-mRNA splicing in plants: characterization of Ser/Arg splicing factors
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27 September 2017
Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains
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PubMed Central
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27 September 2017
Conservation of regulated alternative splicing and identification of functional domains in vertebrate homologs to the Drosophila splicing regulator, suppressor-of-white-apricot
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PubMed Central
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27 September 2017
The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2.
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PubMed Central
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27 September 2017
A splicing enhancer exhibits both constitutive and regulated activities
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
The SR protein B52/SRp55 is essential for Drosophila development
1 reference
stated in
PubMed Central
reference URL
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27 September 2017
Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps
1 reference
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PubMed Central
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27 September 2017
U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements.
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PubMed Central
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27 September 2017
Identification of a plant serine-arginine-rich protein similar to the mammalian splicing factor SF2/ASF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Enhancer-dependent interaction between 5' and 3' splice sites in trans
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors
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PubMed Central
reference URL
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27 September 2017
The human splicing factor ASF/SF2 can specifically recognize pre-mRNA 5' splice sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Primary structure of the human splicing factor asf reveals similarities with drosophila regulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription
1 reference
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PubMed Central
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27 September 2017
The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site
1 reference
stated in
PubMed Central
reference URL
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27 September 2017
General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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27 September 2017
Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability
1 reference
stated in
PubMed Central
reference URL
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27 September 2017
Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.
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27 September 2017
Common themes in the function of transcription and splicing enhancers
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PubMed Central
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27 September 2017
Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans
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PubMed Central
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30 May 2018
Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing
1 reference
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PubMed Central
reference URL
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30 May 2018
The [U4/U6.U5] tri-snRNP-specific 27K protein is a novel SR protein that can be phosphorylated by the snRNP-associated protein kinase
1 reference
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PubMed Central
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30 May 2018
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA.
1 reference
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PubMed Central
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30 May 2018
Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
1 reference
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PubMed Central
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30 May 2018
The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein
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PubMed Central
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30 May 2018
Scanning from an independently specified branch point defines the 3' splice site of mammalian introns
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PubMed Central
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30 May 2018
Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides.
1 reference
stated in
PubMed Central
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30 May 2018
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro
1 reference
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PubMed Central
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30 May 2018
Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells
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PubMed Central
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30 May 2018
Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin.
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PubMed Central
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30 May 2018
An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway
1 reference
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PubMed Central
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30 May 2018
Positive control of pre-mRNA splicing in vitro
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PubMed Central
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30 May 2018
Protein components specifically associated with prespliceosome and spliceosome complexes
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PubMed Central
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30 May 2018
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.
1 reference
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PubMed Central
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29 November 2018
An SC35-like protein and a novel serine/arginine-rich protein interact with Arabidopsis U1-70K protein
1 reference
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PubMed Central
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29 November 2018
Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract.
1 reference
stated in
PubMed Central
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29 November 2018
Protein phosphorylation plays an essential role in the regulation of alternative splicing and sex determination in Drosophila
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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29 November 2018
The plant U1 small nuclear ribonucleoprotein particle 70K protein interacts with two novel serine/arginine-rich proteins
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PubMed Central
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29 November 2018
Role of the constitutive splicing factors U2AF65 and SAP49 in suboptimal RNA splicing of novel retroviral mutants
1 reference
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PubMed Central
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29 November 2018
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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29 November 2018
Distinct functions of SR proteins in alternative pre-mRNA splicing.
1 reference
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PubMed Central
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29 November 2018
SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369994
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29 November 2018
A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10999598
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The cellular organization of gene expression
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SR proteins can compensate for the loss of U1 snRNP functions in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A two-step mechanism for 5' and 3' splice-site pairing
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bimolecular exon ligation by the human spliceosome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10999598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1017/S1355838200000960
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2267700
stated in
Europe PubMed Central
PMC publication ID
1369994
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Fatcat ID
release_sdjj5mnshzgwpaxh7hcqvxiwsq
0 references
OpenCitations bibliographic resource ID
2267700
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2267700
PMC publication ID
1369994
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2267700
stated in
Europe PubMed Central
PMC publication ID
1369994
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
10999598
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2267700
stated in
Europe PubMed Central
PMC publication ID
1369994
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10999598%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ResearchGate publication ID
12322941
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