(Q24291515)

negative regulation of cytokine production

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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L A Schubert

1

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E Jeffery

2

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Y Zhang

3

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F Ramsdell

4

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S F Ziegler

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

5 October 2001

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published in

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volume

276

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issue

40

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page(s)

37672-9

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cites work

The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The mouse homolog of the Wiskott-Aldrich syndrome protein (WASP) gene is highly conserved and maps near the scurfy (sf) mutation on the X chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Five years on the wings of fork head

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The human gp39 promoter. Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The whn transcription factor encoded by the nude locus contains an evolutionarily conserved and functionally indispensable activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Role of the forkhead transcription family member, FKHR, in thymocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Molecular cloning of FKHRL1P2, a member of the developmentally regulated fork head domain transcription factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Role of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

7 January 2021

Suppression of T cell function: a potential role for transcriptional repressor ICER.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

7 January 2021

The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

7 January 2021

The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the proximal X chromosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

7 January 2021

Redox properties of cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104521200

7 January 2021