(Q22009461)

PubMed

PubMed publication ID

10219247

7 February 2023

W Sebald

series ordinal

2

author given names

W

author last names

Sebald

1 reference

PubMed

PubMed publication ID

10219247

7 February 2023

P Reinemer

series ordinal

3

author given names

P

author last names

Reinemer

1 reference

PubMed

PubMed publication ID

10219247

The interleukin-2 and interleukin-4 receptors studied by molecular modelling

7 February 2023

language of work or name

English

0 references

publication date

16 April 1999

0 references

published in

Cell

0 references

volume

97

0 references

issue

2

0 references

page(s)

271-81

0 references

cites work

1 reference

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Crystal structure of a cytokine-binding region of gp130.

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IL-4 and IL-13 receptors: are they one and the same?

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The CCP4 suite: programs for protein crystallography

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A hot spot of binding energy in a hormone-receptor interface

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Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis.

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Eosinophils in allergic reactions.

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Sorting out the cytokines of asthma

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Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.

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A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction

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Requirement for IL-13 independently of IL-4 in experimental asthma

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A model of the complex between interleukin-4 and its receptors

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Crystals of a 1:1 complex between human interleukin-4 and the extracellular domain of its receptor alpha chain

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Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors

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Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation.

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Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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Identification of a critical ligand binding determinant of the human erythropoietin receptor. Evidence for common ligand binding motifs in the cytokine receptor family

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Processing of X-ray diffraction data collected in oscillation mode

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Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy

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Lymphokine production by human T cells in disease states

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Structural comparisons among the short-chain helical cytokines

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

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Global and local determinants for the kinetics of interleukin-4/interleukin-4 receptor alpha chain interaction. A biosensor study employing recombinant interleukin-4-binding protein

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Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency

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A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain

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7 January 2021

Crystal structure of human recombinant interleukin-4 at 2.25 A resolution

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Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor

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