Wikidata

(Q21990155)

English

SRY (sex determining region Y)-box 10

mammalian protein found in Mus musculus

  • dominant megacolon
  • transcription factor SOX-M
  • Protein SOX-21
  • transcription factor SOX-10
  • Sox10
  • SRY-box containing gene 10
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
DNA binding
determination method
IDA
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IEA
retrieved
14 February 2019
stated in
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
cell component
nucleus
determination method
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IEA
retrieved
14 February 2019
stated in
The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IGI
IMP
5 references
retrieved
24 April 2018
stated in
Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
24 April 2018
stated in
Pax3 functions at a nodal point in melanocyte stem cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
24 April 2018
stated in
The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
24 April 2018
stated in
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
24 April 2018
stated in
The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IDA
positive regulation of transcription, DNA-templated
determination method
IDA
IMP
ISO
5 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
ISO
retrieved
24 April 2018
stated in
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
24 April 2018
stated in
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
24 April 2018
stated in
The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
24 April 2018
stated in
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888
determination method
IDA
positive regulation of transcription, DNA-templated
determination method
IDA
IEA
IMP
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
ISO
retrieved
14 February 2019
stated in
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IEA
retrieved
14 February 2019
stated in
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IGI
IMP
6 references
retrieved
14 February 2019
stated in
Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
14 February 2019
stated in
Pax3 functions at a nodal point in melanocyte stem cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
14 February 2019
stated in
The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IGI
retrieved
14 February 2019
stated in
The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IBA
oligodendrocyte differentiation
determination method
IBA
IMP
5 references
retrieved
14 February 2019
stated in
The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
GOA
curator
UniProt
UniProt protein ID
Q04888
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IMP
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888
determination method
IBA

Identifiers

 
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