(Q21984835)

http://www.ebi.ac.uk/interpro/protein/Q9ET47

Ankyrin repeat-containing domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/Q9ET47

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

WH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

IPI

actin filament binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

cell component

stereocilium bundle

1 reference

14 February 2019

The small GTPase Rac1 regulates auditory hair cell morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

1 reference

14 February 2019

dendritic spine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

1 reference

14 February 2019

stereocilium tip

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

1 reference

14 February 2019

actin cytoskeleton

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

ISO

14 February 2019

Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

1 reference

14 February 2019

cytoplasm

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

brush border

The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

ISO

14 February 2019

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

filamentous actin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

3 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

ISO

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

stereocilium tip

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

EXP

biological process

locomotory behavior

IMP

1 reference

14 February 2019

Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

negative regulation of cytoskeleton organization

IMP

1 reference

14 February 2019

Espins are multifunctional actin cytoskeletal regulatory proteins in the microvilli of chemosensory and mechanosensory cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

actin filament network formation

NAS

1 reference

14 February 2019

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

NAS

hearing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

1 reference

14 February 2019

actin filament bundle assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ET47&geneProductId=UniProtKB:Q9ET47

2 references

21 June 2018

21 June 2018

Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ET47&geneProductId=UniProtKB:Q9ET47

parallel actin filament bundle assembly

1 reference

14 February 2019

Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

positive regulation of filopodium assembly

actin filament bundle assembly

IGI

IPI

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

3 references

14 February 2019

14 February 2019

Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ET47

ankyrin repeat-containing domain

has part(s)

1 reference

http://www.ebi.ac.uk/interpro/protein/Q9ET47

WH2 domain

1 reference

http://www.ebi.ac.uk/interpro/protein/Q9ET47

ankyrin repeat

1 reference