(Q21208025)

http://www.ebi.ac.uk/interpro/protein/Q15116

Immunoglobulin-like domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/Q15116

membrane protein

1 reference

inferred from GOA cell component → membrane

Immunoglobulin subtype, protein family

1 reference

inferred from protein domain or family

Immunoglobulin V-set domain, protein family

1 reference

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

7 references

1 January 2018

HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

A secreted protein microarray platform for extracellular protein interaction discovery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 January 2018

Porcine PD-L1: cloning, characterization, and implications during xenotransplantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

signal transducer activity

1 reference

1 January 2018

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15116&geneProductId=UniProtKB:Q15116

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 reference

1 January 2018

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 reference

1 January 2018

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 reference

1 January 2018

external side of plasma membrane

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

positive regulation of apoptotic process

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

multicellular organism development

1 reference

1 January 2018

The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

T cell costimulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 reference

1 January 2018

negative regulation of apoptotic process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

positive regulation of T cell apoptotic process

IDA

1 reference

1 January 2018

Mesenchymal stem cells suppress T cells by inducing apoptosis and through PD-1/B7-H1 interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

IDA

humoral immune response

1 reference

1 January 2018

The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

negative regulation of tolerance induction

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15116

1 reference

1 January 2018

signal transduction

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15116&geneProductId=UniProtKB:Q15116

physically interacts with

pembrolizumab

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3137343

has part(s)

immunoglobulin V-set domain

1 reference

http://www.ebi.ac.uk/interpro/protein/Q15116

immunoglobulin-like domain

1 reference

http://www.ebi.ac.uk/interpro/protein/Q15116

immunoglobulin subtype

1 reference

http://www.ebi.ac.uk/interpro/protein/Q15116

Identifiers

MeSH descriptor ID

D061026

subject named as

Programmed Cell Death 1 Receptor

0 references

MeSH tree code

D12.776.543.750.705.222.875

0 references

D23.050.301.264.894.790

0 references

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

0 references

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023