Wikidata

(Q21127264)

English

SRY-box transcription factor 9

mammalian protein found in Homo sapiens

  • SRY (sex-determining region Y)-box 9 protein
  • SRY-box 9
  • SOX9
  • SRY-related HMG-box, gene 9
  • SRY (sex determining region Y)-box9
  • transcription factor SOX-9
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method or standard
IEA
ISA
ISM
NAS
5 references
retrieved
10 September 2018
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
NAS
retrieved
10 September 2018
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
ISM
retrieved
10 September 2018
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
ISA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IEA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method or standard
IDA
IEA
ISA
ISM
NAS
7 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
NAS
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
ISM
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
ISA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Failure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutations
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method or standard
IBA
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IBA
cell component
nucleus
determination method or standard
IDA
IEA
7 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
27 March 2018
stated in
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
27 March 2018
stated in
RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
27 March 2018
stated in
Sex reversal by loss of the C-terminal transactivation domain of human SOX9
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
27 March 2018
stated in
Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P48436&geneProductId=UniProtKB:P48436
determination method or standard
IDA
nucleus
determination method or standard
IDA
IEA
ISS
9 references
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
Sex reversal by loss of the C-terminal transactivation domain of human SOX9
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
biological process
positive regulation of transcription by RNA polymerase II
determination method or standard
IBA
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IEA
retrieved
8 April 2019
stated in
Sex reversal by loss of the C-terminal transactivation domain of human SOX9
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium
GOA
curator
UniProt
UniProt protein ID
P48436
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Inhibitory role of Notch1 in calcific aortic valve disease
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48436
determination method or standard
IBA

Identifiers

MeSH descriptor ID
D055758
subject named as
SOX9 Transcription Factor
0 references
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21127264&oldid=2023010969"