(Q21114574)

http://www.ebi.ac.uk/interpro/protein/P18505

Gamma-aminobutyric-acid A receptor, beta subunit

1 reference

http://www.ebi.ac.uk/interpro/protein/P18505

Neurotransmitter-gated ion-channel transmembrane domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P18505

Neurotransmitter-gated ion-channel transmembrane domain, protein family

1 reference

inferred from protein domain or family

Neurotransmitter-gated ion-channel ligand-binding domain, protein family

1 reference

inferred from protein domain or family

Neurotransmitter-gated ion-channel, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

anion channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

chloride channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

extracellular ligand-gated ion channel activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

GABA-A receptor activity

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

transmembrane signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

GABA receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

postsynaptic membrane

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

integral component of plasma membrane

3 references

24 April 2018

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

chloride channel complex

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

IDA

GABA-A receptor complex

4 references

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

24 April 2018

Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

24 April 2018

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

integral component of plasma membrane

IDA

4 references

8 April 2019

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

GABA-A receptor complex

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

biological process

response to progesterone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

central nervous system neuron development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

response to toxic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

1 reference

24 April 2018

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

chloride transmembrane transport

TAS

1 reference

8 April 2019

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

gamma-aminobutyric acid signaling pathway

IDA

1 reference

8 April 2019

Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

ion transmembrane transport

IMP

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18505&geneProductId=UniProtKB:P18505

chemical synaptic transmission

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

regulation of membrane potential

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

nervous system process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

regulation of postsynaptic membrane potential

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18505

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4051

language of work or name

English

17 August 2016

metharbital

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL450

zaleplon

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1521

triclofos

positive modulator

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201317

butalbital

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL454

chlordiazepoxide

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL451

diazepam

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL12

prazepam

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL969

zolpidem

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL911

zopiclone

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL135400

topiramate

positive modulator

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL220492

clotiazepam

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1697737

allopregnanolone

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL38856

chlordiazepoxide hydrochloride

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200703

clorazepate dipotassium

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2096631

methohexital sodium

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL30219

pentobarbital sodium

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL971

has part(s)

Neurotransmitter-gated ion-channel transmembrane domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P18505

Neurotransmitter-gated ion-channel ligand-binding domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P18505

Neurotransmitter-gated ion-channel, conserved site

1 reference

http://www.ebi.ac.uk/interpro/protein/P18505

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

Transporter Classification Database ID

1.A.9.5.1

1 reference