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Lymphocyte activating 3
mammalian protein found in Homo sapiens
Protein FDC
lymphocyte activation gene 3 protein
LAG3
lymphocyte-activation gene 3
Lymphocyte Activation Gene 3 Protein
CD223
In more languages
default for all languages
No label defined
No description defined
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18627
part of
interleukin-1 receptor family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18627
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18627
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18627
Immunoglobulin subtype, protein family
1 reference
based on heuristic
inferred from protein domain or family
immunoglobulin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18627
encoded by
LAG3
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18627
molecular function
antigen binding
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
LAG-3, a novel lymphocyte activation gene closely related to CD4
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
TAS
transmembrane signaling receptor activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
MHC class II protein binding
determination method
IDA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
retrieved
1 January 2018
stated in
Characterization of the major histocompatibility complex class II binding site on LAG-3 protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IDA
cell component
membrane
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P18627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
external side of plasma membrane
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P18627
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
plasma membrane
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
TAS
biological process
negative regulation of T cell activation
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
cell surface receptor signaling pathway
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
positive regulation of natural killer cell mediated cytotoxicity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
IEA
antigen processing and presentation of exogenous peptide antigen via MHC class II
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18627
determination method
TAS
has part(s)
immunoglobulin subtype
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18627
immunoglobulin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18627
Identifiers
MeSH descriptor ID
D000093322
subject named as
Lymphocyte Activation Gene 3 Protein
0 references
MeSH tree code
D12.776.465.806
0 references
D12.776.543.750.705.012
0 references
D12.776.543.750.705.222.844
0 references
D23.050.301.264.894.121
0 references
D23.101.100.894.121
0 references
RefSeq protein ID
NP_002277
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3902
XP_011519258
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3902
UniProt protein ID
P18627
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18627
Ensembl protein ID
ENSP00000203629
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000203629
ENSP00000413825
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000413825
UMLS CUI
C5575677
1 reference
based on heuristic
inferred by common MeSH mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
25 May 2023
Sitelinks
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Wikiquote
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Wikisource
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Wikiversity
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Wikivoyage
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Wiktionary
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Multilingual sites
(0 entries)
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