(Q21092773)

Wingless-type MMTV integration site family, member 4

1 reference

Fibroblast growth factor 9

1 reference

Sex determining region of Chr Y

1 reference

sex-determination system

1 reference

9

Robin Lovell-Badge

Robin

Lovell-Badge

1 reference

15 August 2022

3

Ryohei Sekido

Ryohei

Sekido

1 reference

15 August 2022

10

Blanche Capel

Blanche

Capel

1 reference

15 August 2022

8

Richard R

Behringer

Richard R Behringer

1 reference

15 August 2022

Yuna Kim

1

Yuna

Kim

1 reference

15 August 2022

Akio Kobayashi

2

Akio

Kobayashi

1 reference

15 August 2022

Leo DiNapoli

4

Leo

DiNapoli

1 reference

15 August 2022

Jennifer Brennan

5

Jennifer

Brennan

1 reference

15 August 2022

Marie-Christine Chaboissier

6

Marie-Christine

Chaboissier

1 reference

15 August 2022

Francis Poulat

7

Francis

Poulat

1 reference

Creative Commons Attribution 4.0 International

15 August 2022

language of work or name

English

0 references

publication date

June 2006

0 references

published in

PLOS Biology

0 references

volume

4

0 references

issue

6

0 references

page(s)

e187

0 references

copyright license

start time

23 May 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Testis determination requires insulin receptor family function in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Female development in mammals is regulated by Wnt-4 signalling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Dax1 antagonizes Sry action in mammalian sex determination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Functional analysis of Sox8 and Sox9 during sex determination in the mouse

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sox9 induces testis development in XX transgenic mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

A male-specific role for SOX9 in vertebrate sex determination

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Mechanisms underlying differential responses to FGF signaling

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Interactions between Sox9 and beta-catenin control chondrocyte differentiation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sex comes in from the cold: the integration of sex and pattern

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Making a vertebrate limb: new players enter from the wings

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Autosomal XX sex reversal caused by duplication of SOX9.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sertoli cell signaling by Desert hedgehog regulates the male germline

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

The initial phases of testicular organogenesis in the rat. An electron microscopy study.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Expression of the mouse anti-müllerian hormone gene suggests a role in both male and female sexual differentiation.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

In situ analysis of fetal, prepuberal and adult XX—XY chimaeric mouse testes: Sertoli cells are predominantly, but not exclusively, XY

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Meiosis and differentiation of mouse germ cells.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Genetic control of primary sex determination in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Cell proliferation is necessary for the determination of male fate in the gonad

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Male-specific cell migration into the developing gonad.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Entry of mouse embryonic germ cells into meiosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Male development of chromosomally female mice transgenic for Sry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sox9 is sufficient for functional testis development producing fertile male mice in the absence of Sry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y(DOM) sex reversal.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Dax1 expression is dependent on steroidogenic factor 1 in the developing gonad

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Sertoli cell prostaglandin D2 synthetase is a multifunctional molecule: its expression and regulation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463023

Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/16700629

12 December 2020

Male-to-female sex reversal in mice lacking fibroblast growth factor 9

1 reference

https://pubmed.ncbi.nlm.nih.gov/16700629

12 December 2020

Spatially dynamic expression ofSry in mouse genital ridges

1 reference

https://pubmed.ncbi.nlm.nih.gov/16700629

12 December 2020

Cell aggregation precedes the onset of Sox9-expressing preSertoli cells in the genital ridge of mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16700629

12 December 2020

Mesonephric contribution to testis differentiation in the fetal mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16700629

12 December 2020

10.1371/JOURNAL.PBIO.0040187

Identifiers

DOI

1 reference

release_ot7rdzjuyfhojp4g4hfm3gsama

Fatcat ID

0 references

1 reference

1 reference

1 reference