(Q14865240)

http://www.ebi.ac.uk/interpro/protein/P08505

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08505

Interleukin-6/GCSF/MGF, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Induction of endogenous retroviral gene product (SU) as an acute-phase protein by IL-6 in murine hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

interleukin-6 receptor binding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Expression of the murine interleukin 6 receptor in hepatoma cells: the intracytoplasmic domain is not required for interleukin 6 signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

protein binding

IPI

1 reference

9 May 2019

Conservation of structure and function between human and murine IL-16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

external side of plasma membrane

IPI

cell component

1 reference

9 May 2019

Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

extracellular space

25 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Endocrine regulation of energy metabolism by the skeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

An extraribosomal function of ribosomal protein L13a in macrophages resolves inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Altered cytokine production in mice lacking P2X(7) receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Accessory protein-like is essential for IL-18-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Negative regulation of Toll-like-receptor signaling by IRF-4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Interleukin-1, interleukin-6, and tumor necrosis factor alpha are produced in the mouse uterus during the estrous cycle and are induced by estrogen and progesterone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Adenosine receptors in regulation of dendritic cell differentiation and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

interleukin-6 receptor complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

biological process

response to yeast

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to amino acid

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

muscle cell cellular homeostasis

1 reference

9 May 2019

Interleukin-6 and cachexia in ApcMin/+ mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to heat

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

endocrine pancreas development

1 reference

9 May 2019

Interleukin-6 regulates pancreatic alpha-cell mass expansion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

branching involved in salivary gland morphogenesis

regulation of apoptotic process

1 reference

9 May 2019

Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to cytokine

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

glucose homeostasis

1 reference

9 May 2019

NCOA5 haploinsufficiency results in glucose intolerance and subsequent hepatocellular carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to antibiotic

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

myeloid cell homeostasis

1 reference

9 May 2019

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to mechanical stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to insulin

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

glucagon secretion

1 reference

9 May 2019

Interleukin-6 regulates pancreatic alpha-cell mass expansion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to nutrient levels

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to caffeine

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

negative regulation of hormone secretion

1 reference

9 May 2019

Inhibition of growth hormone-releasing factor production in mouse placenta by cytokines using gp130 as a signal transducer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

T cell activation

1 reference

9 May 2019

Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of epithelial cell proliferation

cellular response to hepatocyte growth factor stimulus

1 reference

9 May 2019

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

wound healing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to electrical stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to dexamethasone stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to calcium ion

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to lipopolysaccharide

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

acute-phase response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

1 reference

9 May 2019

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

1 reference

9 May 2019

defense response to protozoan

1 reference

9 May 2019

Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to bacterium

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to organic cyclic compound

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

epithelial cell proliferation involved in salivary gland morphogenesis

1 reference

9 May 2019

Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

human ageing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of cell proliferation in bone marrow

1 reference

9 May 2019

Parathyroid hormone mediates hematopoietic cell expansion through interleukin-6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

T-helper 17 cell lineage commitment

1 reference

8 April 2019

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of gene expression

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

regulation of cell population proliferation

1 reference

9 May 2019

Interleukin-6 and cachexia in ApcMin/+ mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

bone remodeling

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of T-helper 2 cell differentiation

1 reference

9 May 2019

Inhibition of Th2 differentiation and GATA-3 expression by BCL-6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to auditory stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to cold

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to lipopolysaccharide

SASH1 is a scaffold molecule in endothelial TLR4 signaling

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to estradiol stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

acute inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to prolactin

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of T-helper 2 cell cytokine production

1 reference

9 May 2019

Interleukin-6 deficiency increases inflammatory bone destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

negative regulation of interleukin-1-mediated signaling pathway

1 reference

9 May 2019

Interleukin-6 deficiency increases inflammatory bone destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to cytokine stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cellular response to nutrient levels

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

negative regulation of bone resorption

1 reference

9 May 2019

Interleukin-6 deficiency increases inflammatory bone destruction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

lymphocyte costimulation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

neutrophil apoptotic process

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

hepatic immune response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of acute inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

inflammatory response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of cell population proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

regulation of vascular endothelial growth factor production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

cytokine-mediated signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

neuron projection development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of chemokine production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of interleukin-6 production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

negative regulation of collagen biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of peptidyl-serine phosphorylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of T cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

negative regulation of apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of MAPK cascade

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of translation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of transcription by RNA polymerase II

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of smooth muscle cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of B cell activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of DNA-binding transcription factor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

response to glucocorticoid

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

defense response to virus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

interleukin-6-mediated signaling pathway

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

Expression of the murine interleukin 6 receptor in hepatoma cells: the intracytoplasmic domain is not required for interleukin 6 signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

9 May 2019

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of glial cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of gliogenesis

1 reference

9 May 2019

miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of epithelial to mesenchymal transition

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of extracellular matrix disassembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of vascular endothelial growth factor production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of osteoblast differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

positive regulation of apoptotic DNA fragmentation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505

Interleukin-6/GCSF/MGF, conserved site

has part(s)

1 reference

InterPro Release 71.0