(Q14864699)

http://www.ebi.ac.uk/interpro/protein/P01132

Pro-epidermal growth factor

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

Growth factor receptor cysteine-rich domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

membrane protein

1 reference

inferred from GOA cell component → membrane

EGF-like calcium-binding domain, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

LDLR class B repeat, protein family

1 reference

EGF-like calcium-binding, conserved site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

1 reference

14 February 2019

Wnt-protein binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

protein binding

IPI

1 reference

14 February 2019

SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

Wnt-activated receptor activity

IPI

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

growth factor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

protein tyrosine kinase activity

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01132&geneProductId=UniProtKB:P01132

epidermal growth factor receptor binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

1 reference

14 February 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

1 reference

14 February 2019

receptor complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

1 reference

14 February 2019

intracellular anatomical structure

TAS

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01132&geneProductId=UniProtKB:P01132

extracellular space

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

An inborn error in epidermal growth factor prohormone metabolism in a mouse model of autosomal recessive polycystic kidney disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

3 references

14 February 2019

TAS

14 February 2019

SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

regulation of protein transport

biological process

1 reference

14 February 2019

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

mammary gland alveolus development

1 reference

14 February 2019

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of ubiquitin-dependent protein catabolic process

1 reference

14 February 2019

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

Wnt signaling pathway involved in dorsal/ventral axis specification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01132&geneProductId=UniProtKB:P01132

1 reference

24 April 2018

positive regulation of cell population proliferation

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of cerebellar granule cell precursor proliferation

1 reference

14 February 2019

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

canonical Wnt signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

negative regulation of cholesterol efflux

1 reference

14 February 2019

Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

N-Acetylglucosaminyltransferase V Expression Levels Regulate Cadherin-associated Homotypic Cell-Cell Adhesion and Intracellular Signaling Pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of DNA binding

1 reference

14 February 2019

Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

branching morphogenesis of an epithelial tube

1 reference

14 February 2019

Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of protein tyrosine kinase activity

1 reference

14 February 2019

Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

embryonic retina morphogenesis in camera-type eye

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01132&geneProductId=UniProtKB:P01132

1 reference

24 April 2018

regulation of receptor signaling pathway via JAK-STAT

1 reference

14 February 2019

Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

epidermal growth factor receptor signaling pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

14 February 2019

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of fibroblast proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

regulation of protein secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of DNA biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01132

positive regulation of protein localization to early endosome

Ensembl genome database project

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01132&geneProductId=UniProtKB:P01132

EGF-like calcium-binding, conserved site

has part(s)

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

EGF-like calcium-binding domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

LDLR class B repeat

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

EGF-like, conserved site

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

EGF-type aspartate/asparagine hydroxylation site

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

EGF-like domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P01132

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016