The following pages link to Leucine rich repeat kinase 2 (Q409961):
Displaying 50 items.
- LRRK2 (Q15331136) (← links)
- (Q21109320) (redirect page) (← links)
- GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1 (Q21144926) (← links)
- Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity (Q22254785) (← links)
- LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool (Q24292798) (← links)
- Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice (Q24293070) (← links)
- Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP (Q24293723) (← links)
- LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress (Q24294466) (← links)
- Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system (Q24294684) (← links)
- GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease (Q24294785) (← links)
- LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6 (Q24296778) (← links)
- The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity (Q24297634) (← links)
- Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers (Q24298093) (← links)
- LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex (Q24298891) (← links)
- LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins (Q24300440) (← links)
- The R1441C mutation of LRRK2 disrupts GTP hydrolysis (Q24303406) (← links)
- Kinase activity of mutant LRRK2 mediates neuronal toxicity (Q24303603) (← links)
- Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export (Q24303851) (← links)
- Dominant-negative effects of LRRK2 heterodimers: a possible mechanism of neurodegeneration in Parkinson's disease caused by LRRK2 I2020T mutation (Q24305419) (← links)
- ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2 (Q24305448) (← links)
- GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2 (Q24306167) (← links)
- Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant (Q24306788) (← links)
- Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition (Q24307004) (← links)
- LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study (Q24307455) (← links)
- ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2 (Q24307742) (← links)
- The role of oxidative stress in Parkinson's disease (Q24307946) (← links)
- Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7 (Q24309417) (← links)
- A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation (Q24310126) (← links)
- Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment (Q24310262) (← links)
- Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications (Q24310608) (← links)
- The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites (Q24313336) (← links)
- RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk (Q24315688) (← links)
- Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation (Q24316270) (← links)
- LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junction (Q24316894) (← links)
- Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways (Q24316917) (← links)
- The familial Parkinsonism gene LRRK2 regulates neurite process morphology (Q24317613) (← links)
- Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice (Q24317631) (← links)
- LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25 (Q24317760) (← links)
- Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies (Q24318474) (← links)
- The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation (Q24318533) (← links)
- Localization of LRRK2 to membranous and vesicular structures in mammalian brain (Q24318643) (← links)
- The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro (Q24322792) (← links)
- LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity (Q24323196) (← links)
- Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death (Q24323228) (← links)
- Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans (Q24324231) (← links)
- Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease (Q24336432) (← links)
- Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease (Q24336655) (← links)
- LRRK2, but not pathogenic mutants, protects against H2O2 stress depending on mitochondrial function and endocytosis in a yeast model (Q24338346) (← links)
- Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity (Q24338647) (← links)
- Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain (Q24338665) (← links)