- Was a close and dear friend of legendary Cuban singer La Lupe. When she passed away, Colon provided a sizable amount of the funds needed to purchase her headstone.
- Founder of the Puerto Rican Traveling Theater in New York City.
- Was actually only ten years older than Al Pacino when she played his mother in Scarface (1983).
- Lifetime member of the Actors' Studio.
- She made guest appearances on both of the longest-running prime time dramas in US television history: Gunsmoke (1955) and Law & Order (1990).
- She was awarded the National Medal of the Arts in 2015 for her services and contribution to theatre.
- Acted alongside both Godfathers from The Godfather I and II.
- Has been in two movies with Marlon Brando, both westerns: The Appaloosa (1966) and One-Eyed Jacks (1961).
- Survived by her husband Fred, stepson Fabian Valle, stepdaughter Wendy Valle, and four grandchildren.
- She played an ingenue in several low budget crime films and programs from 20th Century Fox during the 1960's including Thunder Island and Harbor Lights.
- She played a handicapped character on Guiding Light (1952).
- Upon her death, she was cremated and her ashes returned to her husband.
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