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- DirectorMichel GondryStarsJim CarreyKate WinsletTom WilkinsonWhen their relationship turns sour, a couple undergoes a medical procedure to have each other erased from their memories forever.
- DirectorStephen ChboskyStarsLogan LermanEmma WatsonEzra MillerCharlie, a 15-year-old introvert, enters high school and is nervous about his new life. When he befriends his seniors, he learns to cope with his friend's suicide and his tumultuous past.
- DirectorSofia CoppolaStarsKirsten DunstJosh HartnettJames WoodsA group of male friends become obsessed with five mysterious sisters who are sheltered by their strict, religious parents in suburban Detroit in the mid 1970s.
- DirectorDestin Daniel CrettonStarsBrie LarsonFrantz TurnerJohn Gallagher Jr.A 20-something supervising staff member of a residential treatment facility navigates the troubled waters of that world alongside her co-worker and longtime boyfriend.
- DirectorDarren AronofskyStarsNatalie PortmanMila KunisVincent CasselNina is a talented but unstable ballerina on the verge of stardom. Pushed to the breaking point by her artistic director and a seductive rival, Nina's grip on reality slips, plunging her into a waking nightmare.
- DirectorKaran JoharStarsShah Rukh KhanKajolSheetal MenonRizwan Khan is a Muslim immigrant to the US with Asperger's syndrome. After his family falls apart in the aftermath of 9/11, he begins an epic quest across the country to speak to the President of the United States and clear his name.
- DirectorBarry LevinsonStarsDustin HoffmanTom CruiseValeria GolinoAfter a selfish L.A. yuppie learns his estranged father left a fortune to an autistic-savant brother in Ohio that he didn't know existed, he absconds with his brother and sets out across the country, hoping to gain a larger inheritance.
- DirectorPeter WernerStarsKristen BellDiane LaddShedrack Anderson IIIA teenage girl tries to raise her three half-brothers and one half-sister on her own after their drug-addicted mother is sent to jail.
- DirectorMichael Ray RhodesStarsSarah Jessica ParkerSally StruthersLexi RandallFact-based story of a legal battle fought over custody of five siblings.
- DirectorLee DanielsStarsGabourey SidibeMo'NiquePaula PattonIn New York City's Harlem circa 1987, an overweight, abused, illiterate teen who is pregnant with her second child is invited to enroll in an alternative school in hopes that she can re-route her life in a better direction.
- DirectorJessica SharzerStarsKristen StewartElizabeth PerkinsRichard HagermanA teenager is traumatized into silence after a disastrous summer party.
- DirectorPeter KosminskyStarsMichelle PfeifferRenée ZellwegerRobin WrightA teenager journeys through a series of foster homes after her mother goes to prison for committing a crime of passion.
- DirectorMike BinderStarsAdam SandlerDon CheadleJada Pinkett SmithA man who lost his family in the September 11 attack on New York City runs into his old college roommate. Rekindling the friendship is the one thing that appears able to help the man recover from his grief.
- DirectorMax MayerStarsHugh DancyRose ByrnePeter GallagherAdam, a lonely man with Asperger's Syndrome, develops a relationship with his upstairs neighbor, Beth.
- DirectorRobert ZemeckisStarsTom HanksRobin WrightGary SiniseThe history of the United States from the 1950s to the '70s unfolds from the perspective of an Alabama man with an IQ of 75, who yearns to be reunited with his childhood sweetheart.
- DirectorOlivier NakacheÉric ToledanoStarsFrançois CluzetOmar SyAnne Le NyAfter he becomes a quadriplegic from a paragliding accident, an aristocrat hires a young man from the projects to be his caregiver.
- DirectorGus Van SantStarsJoaquin PhoenixJonah HillRooney MaraOn the rocky path to sobriety after a life-changing accident, John Callahan discovers the healing power of art, willing his injured hands into drawing hilarious, often controversial cartoons, which bring him a new lease on life.
- DirectorNeil BurgerStarsKevin HartBryan CranstonNicole KidmanA comedic look at the relationship between a wealthy man with quadriplegia and an unemployed man with a criminal record who's hired to help him.
- DirectorFabien ConstantStarsSarah Jessica ParkerSimon BakerGus BirneyA singer (Sarah Jessica Parker) in New York City gets a grim diagnosis that puts her life and dreams into perspective.
- DirectorZack SnyderStarsEmily BrowningVanessa HudgensAbbie CornishA young girl institutionalized by her abusive stepfather retreats to an alternative reality as a coping strategy and envisions a plan to help her escape.
- DirectorJeremy LevenStarsJohnny DeppMarlon BrandoFaye DunawayA psychiatrist must cure a young patient who presents himself as Don Juan, the world's greatest lover.
- DirectorJordan MelamedStarsJoseph Gordon-LevittMichael BacallZooey DeschanelAfter attacking another player with a bat during baseball at school, Lyle's sent to the psych ward. He meets other teenagers with problems. Will group therapy help?
- DirectorAndrew HaighStarsCharlie PlummerAmy SeimetzTravis FimmelA teenager gets a summer job working for a horse trainer and befriends the fading racehorse, Lean on Pete.
- DirectorArthur Allan SeidelmanStarsNancy McKeonValerie HarperStephen MachtA family begins to fall apart when they find out their eldest daughter, Nicole, is a victim of schizophrenia.
- DirectorTony BillStarsSissy SpacekAlfre WoodardJodelle FerlandA troubled foster child with an affinity for drawing and artwork, becomes attached to her eccentric and forgetful new foster mother, also an artist.